Analysis of Tumor-Infiltrating T-Cell Transcriptomes Reveal a Unique Genetic Signature across Different Types of Cancer

Analysis of Tumor-Infiltrating T-Cell Transcriptomes Reveal a Unique Genetic Signature across Different Types of Cancer

CD8+ and CD4+ T-cells play a key role in cellular immune responses against cancer by cytotoxic responses and effector lineages differentiation, respectively. These subsets have been found in different types of cancer; however, it is unclear whether tumor-infiltrating T-cell subsets exhibit similar t...

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Bibliographic Details
Main Authors: Mabel Vidal, Marco Fraga, Faryd Llerena, Agustín Vera, Mauricio Hernández, Elard Koch, Felipe Reyes-López, Eva Vallejos-Vidal, Guillermo Cabrera-Vives, Estefanía Nova-Lamperti
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
single-cell RNA-seq
cancer
T-cell
immunopathology
metabolic pathways
viral pathways
Online Access:https://www.mdpi.com/1422-0067/23/19/11065

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