Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes
A simple and efficient method for the synthesis of spiropyridazine-benzosultams has been developed by means of [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes. This approach displays advantages such as mild reaction conditions, wide substrate rang...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2024-02-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.20.29 |
| _version_ | 1797277010362368000 |
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| author | Wenqing Hao Long Wang Jinlei Zhang Dawei Teng Guorui Cao |
| author_facet | Wenqing Hao Long Wang Jinlei Zhang Dawei Teng Guorui Cao |
| author_sort | Wenqing Hao |
| collection | DOAJ |
| description | A simple and efficient method for the synthesis of spiropyridazine-benzosultams has been developed by means of [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes. This approach displays advantages such as mild reaction conditions, wide substrate range tolerance, simple operation, compatibility with gram-scale preparation. |
| first_indexed | 2024-03-07T15:41:32Z |
| format | Article |
| id | doaj.art-4d25e0c858d24ef78950c0e2c621939d |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-03-07T15:41:32Z |
| publishDate | 2024-02-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-4d25e0c858d24ef78950c0e2c621939d2024-03-05T08:45:43ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972024-02-0120128028610.3762/bjoc.20.291860-5397-20-29Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienesWenqing Hao0Long Wang1Jinlei Zhang2Dawei Teng3Guorui Cao4College of Chemical Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Lu, Qingdao 266042, China College of Chemical Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Lu, Qingdao 266042, China College of Chemical Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Lu, Qingdao 266042, China College of Chemical Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Lu, Qingdao 266042, China College of Chemical Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Lu, Qingdao 266042, China A simple and efficient method for the synthesis of spiropyridazine-benzosultams has been developed by means of [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes. This approach displays advantages such as mild reaction conditions, wide substrate range tolerance, simple operation, compatibility with gram-scale preparation.https://doi.org/10.3762/bjoc.20.29[4 + 2] annulation reaction1,2-diaza-1,3-dienesspiro-benzosultams3-substituted benzoisothiazole 1,1-dioxides |
| spellingShingle | Wenqing Hao Long Wang Jinlei Zhang Dawei Teng Guorui Cao Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes Beilstein Journal of Organic Chemistry [4 + 2] annulation reaction 1,2-diaza-1,3-dienes spiro-benzosultams 3-substituted benzoisothiazole 1,1-dioxides |
| title | Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes |
| title_full | Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes |
| title_fullStr | Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes |
| title_full_unstemmed | Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes |
| title_short | Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes |
| title_sort | synthesis of spiropyridazine benzosultams by the 4 2 annulation reaction of 3 substituted benzoisothiazole 1 1 dioxides with 1 2 diaza 1 3 dienes |
| topic | [4 + 2] annulation reaction 1,2-diaza-1,3-dienes spiro-benzosultams 3-substituted benzoisothiazole 1,1-dioxides |
| url | https://doi.org/10.3762/bjoc.20.29 |
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