Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case
Ictal fear—a relatively rare phenomenon—is a semiological characteristic of epilepsy. Most patients with epilepsy with ictal fear have an epileptic zone in the mesial temporal lobe, which is the classical brain area involved in emotion processing. Herein, we report a case of epilepsy with ictal fear...
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Frontiers Media S.A.
2018-08-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.00644/full |
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| author | Jing Wang Qian Wang Mengyang Wang Guoming Luan Guoming Luan Guoming Luan Jian Zhou Yuguang Guan Zhaofen Yan |
| author_facet | Jing Wang Qian Wang Mengyang Wang Guoming Luan Guoming Luan Guoming Luan Jian Zhou Yuguang Guan Zhaofen Yan |
| author_sort | Jing Wang |
| collection | DOAJ |
| description | Ictal fear—a relatively rare phenomenon—is a semiological characteristic of epilepsy. Most patients with epilepsy with ictal fear have an epileptic zone in the mesial temporal lobe, which is the classical brain area involved in emotion processing. Herein, we report a case of epilepsy with ictal fear as the first manifestation in a 10-year-old boy. All noninvasive evaluation including scalp video electroencephalography (EEG), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET-CT) suggested a possible lesion in the left posterior brain region. Stereo-electroencephalography (sEEG) results showed high frequency direct current shift in the left occipital lobe 1 s before the fear manifestation which preceded in 12 s the discharge in the amygdala. This case highlights the epileptic network hypothesis which suggested occipital cortex may play an important role in the early emotional network independently of amygdala activation. |
| first_indexed | 2024-12-24T05:34:55Z |
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| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-24T05:34:55Z |
| publishDate | 2018-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neurology |
| spelling | doaj.art-4d299f634bf443df8a6b9cb905fb46ab2022-12-21T17:13:03ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-08-01910.3389/fneur.2018.00644404381Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) CaseJing Wang0Qian Wang1Mengyang Wang2Guoming Luan3Guoming Luan4Guoming Luan5Jian Zhou6Yuguang Guan7Zhaofen Yan8Department of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaDepartment of Clinical Psychology, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaDepartment of Functional Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaBeijing Key Laboratory of Epilepsy, Epilepsy Center, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaBeijing Institute for Brain Disorders, Beijing, ChinaDepartment of Functional Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaDepartment of Functional Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing, ChinaIctal fear—a relatively rare phenomenon—is a semiological characteristic of epilepsy. Most patients with epilepsy with ictal fear have an epileptic zone in the mesial temporal lobe, which is the classical brain area involved in emotion processing. Herein, we report a case of epilepsy with ictal fear as the first manifestation in a 10-year-old boy. All noninvasive evaluation including scalp video electroencephalography (EEG), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET-CT) suggested a possible lesion in the left posterior brain region. Stereo-electroencephalography (sEEG) results showed high frequency direct current shift in the left occipital lobe 1 s before the fear manifestation which preceded in 12 s the discharge in the amygdala. This case highlights the epileptic network hypothesis which suggested occipital cortex may play an important role in the early emotional network independently of amygdala activation.https://www.frontiersin.org/article/10.3389/fneur.2018.00644/fullstereo-electroencephalography (sEEG)epilepsyictal fearoccipital cortexfocal cortical dysplasia (FCD) |
| spellingShingle | Jing Wang Qian Wang Mengyang Wang Guoming Luan Guoming Luan Guoming Luan Jian Zhou Yuguang Guan Zhaofen Yan Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case Frontiers in Neurology stereo-electroencephalography (sEEG) epilepsy ictal fear occipital cortex focal cortical dysplasia (FCD) |
| title | Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case |
| title_full | Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case |
| title_fullStr | Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case |
| title_full_unstemmed | Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case |
| title_short | Occipital Lobe Epilepsy With Ictal Fear: Evidence From a Stereo-Electroencephalography (sEEG) Case |
| title_sort | occipital lobe epilepsy with ictal fear evidence from a stereo electroencephalography seeg case |
| topic | stereo-electroencephalography (sEEG) epilepsy ictal fear occipital cortex focal cortical dysplasia (FCD) |
| url | https://www.frontiersin.org/article/10.3389/fneur.2018.00644/full |
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