Incidence and mortality rates of strokes in Kazakhstan in 2014–2019
Abstract There is a lack of information on the epidemiology of acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) in developing countries. This research presents incidence and mortality rates of stroke patients based on hospital admission and discharge sta...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-20302-8 |
| _version_ | 1811202828770738176 |
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| author | Gulnur Zhakhina Bakhytbek Zhalmagambetov Arnur Gusmanov Yesbolat Sakko Sauran Yerdessov Elzar Matmusaeva Aliya Imanova Byron Crape Antonio Sarria-Santamera Abduzhappar Gaipov |
| author_facet | Gulnur Zhakhina Bakhytbek Zhalmagambetov Arnur Gusmanov Yesbolat Sakko Sauran Yerdessov Elzar Matmusaeva Aliya Imanova Byron Crape Antonio Sarria-Santamera Abduzhappar Gaipov |
| author_sort | Gulnur Zhakhina |
| collection | DOAJ |
| description | Abstract There is a lack of information on the epidemiology of acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) in developing countries. This research presents incidence and mortality rates of stroke patients based on hospital admission and discharge status in one of the Central Asian countries by analysis of large-scale healthcare data. The registry data of 177,947 patients admitted to the hospital with the diagnosis of stroke between 2014 and 2019 were extracted from the National Electronic Health System of Kazakhstan. We provide descriptive statistics and analyze the association of socio-demographic and medical characteristics such as comorbidities and surgical treatments. Among all stroke patients, the incidence rate based on hospital admission of AIS was significantly higher compared to SAH and ICH patients. In 5 year follow-up period, AIS patients had a better outcome than SAH and ICH patients (64.7, 63.1 and 57.3% respectively). The hazard ratio (HR) after the trepanation and decompression surgery was 2.3 and 1.48 for AIS and SAH patients; however, it was protective for ICH (HR = 0.87). The investigation evaluated an increase in the all-cause mortality rates based on the discharge status of stroke patients, while the incidence rate decreased over time. |
| first_indexed | 2024-04-12T02:45:12Z |
| format | Article |
| id | doaj.art-4d2aa88cf139439a9cd556e973860aaf |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-12T02:45:12Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-4d2aa88cf139439a9cd556e973860aaf2022-12-22T03:51:11ZengNature PortfolioScientific Reports2045-23222022-09-0112111210.1038/s41598-022-20302-8Incidence and mortality rates of strokes in Kazakhstan in 2014–2019Gulnur Zhakhina0Bakhytbek Zhalmagambetov1Arnur Gusmanov2Yesbolat Sakko3Sauran Yerdessov4Elzar Matmusaeva5Aliya Imanova6Byron Crape7Antonio Sarria-Santamera8Abduzhappar Gaipov9Department of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineDepartment of Neurology, Multidisciplinary City Hospital #2Department of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineDepartment of Medicine, Nazarbayev University School of MedicineAbstract There is a lack of information on the epidemiology of acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) in developing countries. This research presents incidence and mortality rates of stroke patients based on hospital admission and discharge status in one of the Central Asian countries by analysis of large-scale healthcare data. The registry data of 177,947 patients admitted to the hospital with the diagnosis of stroke between 2014 and 2019 were extracted from the National Electronic Health System of Kazakhstan. We provide descriptive statistics and analyze the association of socio-demographic and medical characteristics such as comorbidities and surgical treatments. Among all stroke patients, the incidence rate based on hospital admission of AIS was significantly higher compared to SAH and ICH patients. In 5 year follow-up period, AIS patients had a better outcome than SAH and ICH patients (64.7, 63.1 and 57.3% respectively). The hazard ratio (HR) after the trepanation and decompression surgery was 2.3 and 1.48 for AIS and SAH patients; however, it was protective for ICH (HR = 0.87). The investigation evaluated an increase in the all-cause mortality rates based on the discharge status of stroke patients, while the incidence rate decreased over time.https://doi.org/10.1038/s41598-022-20302-8 |
| spellingShingle | Gulnur Zhakhina Bakhytbek Zhalmagambetov Arnur Gusmanov Yesbolat Sakko Sauran Yerdessov Elzar Matmusaeva Aliya Imanova Byron Crape Antonio Sarria-Santamera Abduzhappar Gaipov Incidence and mortality rates of strokes in Kazakhstan in 2014–2019 Scientific Reports |
| title | Incidence and mortality rates of strokes in Kazakhstan in 2014–2019 |
| title_full | Incidence and mortality rates of strokes in Kazakhstan in 2014–2019 |
| title_fullStr | Incidence and mortality rates of strokes in Kazakhstan in 2014–2019 |
| title_full_unstemmed | Incidence and mortality rates of strokes in Kazakhstan in 2014–2019 |
| title_short | Incidence and mortality rates of strokes in Kazakhstan in 2014–2019 |
| title_sort | incidence and mortality rates of strokes in kazakhstan in 2014 2019 |
| url | https://doi.org/10.1038/s41598-022-20302-8 |
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