Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria

Chronic lymphocytic leukemia (CLL) is a rare hematologic disorder with affected patients having complications of frequent infections and possible transformation to a more aggressive malignancy. The occurrence of CLL in the bladder is a rare event, with few reported cases. As a result, its aggressive...

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Main Authors: Vikas Desai, Sudhir Isharwal, Aydin Pooli, Subodh Lele, Michael Feloney
Format: Article
Language:English
Published: SAGE Publishing 2014-10-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287214535461
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author Vikas Desai
Sudhir Isharwal
Aydin Pooli
Subodh Lele
Michael Feloney
author_facet Vikas Desai
Sudhir Isharwal
Aydin Pooli
Subodh Lele
Michael Feloney
author_sort Vikas Desai
collection DOAJ
description Chronic lymphocytic leukemia (CLL) is a rare hematologic disorder with affected patients having complications of frequent infections and possible transformation to a more aggressive malignancy. The occurrence of CLL in the bladder is a rare event, with few reported cases. As a result, its aggressiveness and the optimal course for treatment are unknown. Despite this, its presence in the bladder warrants continued surveillance, as recurrence and progression to other bladder malignancies are possible. We present a 71-year-old woman initially diagnosed with CLL who was plagued by recurrent hematuria and dysuria for over a decade, which lead to multiple negative urologic workups. However, these continued workups eventually lead to her diagnosis of bladder CLL with a subsequent finding of carcinoma in situ that was prompted by a suspicious surveillance cystoscopy performed 4 months after her initial bladder diagnosis. Hence, infiltration of CLL in the urinary bladder merits close follow up, including additional urologic procedures.
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spelling doaj.art-4d2bcdb891574dfbaea24eb4e8eab6852022-12-22T01:37:49ZengSAGE PublishingTherapeutic Advances in Urology1756-28721756-28802014-10-01610.1177/1756287214535461Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuriaVikas DesaiSudhir IsharwalAydin PooliSubodh LeleMichael FeloneyChronic lymphocytic leukemia (CLL) is a rare hematologic disorder with affected patients having complications of frequent infections and possible transformation to a more aggressive malignancy. The occurrence of CLL in the bladder is a rare event, with few reported cases. As a result, its aggressiveness and the optimal course for treatment are unknown. Despite this, its presence in the bladder warrants continued surveillance, as recurrence and progression to other bladder malignancies are possible. We present a 71-year-old woman initially diagnosed with CLL who was plagued by recurrent hematuria and dysuria for over a decade, which lead to multiple negative urologic workups. However, these continued workups eventually lead to her diagnosis of bladder CLL with a subsequent finding of carcinoma in situ that was prompted by a suspicious surveillance cystoscopy performed 4 months after her initial bladder diagnosis. Hence, infiltration of CLL in the urinary bladder merits close follow up, including additional urologic procedures.https://doi.org/10.1177/1756287214535461
spellingShingle Vikas Desai
Sudhir Isharwal
Aydin Pooli
Subodh Lele
Michael Feloney
Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
Therapeutic Advances in Urology
title Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
title_full Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
title_fullStr Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
title_full_unstemmed Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
title_short Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
title_sort chronic lymphocytic leukemia of the bladder an atypical etiology of gross hematuria
url https://doi.org/10.1177/1756287214535461
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