Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria
Chronic lymphocytic leukemia (CLL) is a rare hematologic disorder with affected patients having complications of frequent infections and possible transformation to a more aggressive malignancy. The occurrence of CLL in the bladder is a rare event, with few reported cases. As a result, its aggressive...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2014-10-01
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Series: | Therapeutic Advances in Urology |
Online Access: | https://doi.org/10.1177/1756287214535461 |
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author | Vikas Desai Sudhir Isharwal Aydin Pooli Subodh Lele Michael Feloney |
author_facet | Vikas Desai Sudhir Isharwal Aydin Pooli Subodh Lele Michael Feloney |
author_sort | Vikas Desai |
collection | DOAJ |
description | Chronic lymphocytic leukemia (CLL) is a rare hematologic disorder with affected patients having complications of frequent infections and possible transformation to a more aggressive malignancy. The occurrence of CLL in the bladder is a rare event, with few reported cases. As a result, its aggressiveness and the optimal course for treatment are unknown. Despite this, its presence in the bladder warrants continued surveillance, as recurrence and progression to other bladder malignancies are possible. We present a 71-year-old woman initially diagnosed with CLL who was plagued by recurrent hematuria and dysuria for over a decade, which lead to multiple negative urologic workups. However, these continued workups eventually lead to her diagnosis of bladder CLL with a subsequent finding of carcinoma in situ that was prompted by a suspicious surveillance cystoscopy performed 4 months after her initial bladder diagnosis. Hence, infiltration of CLL in the urinary bladder merits close follow up, including additional urologic procedures. |
first_indexed | 2024-12-10T18:35:11Z |
format | Article |
id | doaj.art-4d2bcdb891574dfbaea24eb4e8eab685 |
institution | Directory Open Access Journal |
issn | 1756-2872 1756-2880 |
language | English |
last_indexed | 2024-12-10T18:35:11Z |
publishDate | 2014-10-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Therapeutic Advances in Urology |
spelling | doaj.art-4d2bcdb891574dfbaea24eb4e8eab6852022-12-22T01:37:49ZengSAGE PublishingTherapeutic Advances in Urology1756-28721756-28802014-10-01610.1177/1756287214535461Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuriaVikas DesaiSudhir IsharwalAydin PooliSubodh LeleMichael FeloneyChronic lymphocytic leukemia (CLL) is a rare hematologic disorder with affected patients having complications of frequent infections and possible transformation to a more aggressive malignancy. The occurrence of CLL in the bladder is a rare event, with few reported cases. As a result, its aggressiveness and the optimal course for treatment are unknown. Despite this, its presence in the bladder warrants continued surveillance, as recurrence and progression to other bladder malignancies are possible. We present a 71-year-old woman initially diagnosed with CLL who was plagued by recurrent hematuria and dysuria for over a decade, which lead to multiple negative urologic workups. However, these continued workups eventually lead to her diagnosis of bladder CLL with a subsequent finding of carcinoma in situ that was prompted by a suspicious surveillance cystoscopy performed 4 months after her initial bladder diagnosis. Hence, infiltration of CLL in the urinary bladder merits close follow up, including additional urologic procedures.https://doi.org/10.1177/1756287214535461 |
spellingShingle | Vikas Desai Sudhir Isharwal Aydin Pooli Subodh Lele Michael Feloney Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria Therapeutic Advances in Urology |
title | Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria |
title_full | Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria |
title_fullStr | Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria |
title_full_unstemmed | Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria |
title_short | Chronic lymphocytic leukemia of the bladder: an atypical etiology of gross hematuria |
title_sort | chronic lymphocytic leukemia of the bladder an atypical etiology of gross hematuria |
url | https://doi.org/10.1177/1756287214535461 |
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