Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia
Nutritional status could affect clinical outcomes in critical patients. We aimed to determine the prognostic accuracy of the modified Nutrition Risk in Critically Ill (mNUTRIC) score for hospital mortality and treatment outcomes in patients with severe community-acquired pneumonia (SCAP) compared to...
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MDPI AG
2021-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/1/198 |
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| author | Chia-Cheng Tseng Chih-Yen Tu Chia-Hung Chen Yao-Tung Wang Wei-Chih Chen Pin-Kuei Fu Chin-Ming Chen Chih-Cheng Lai Li-Kuo Kuo Shih-Chi Ku Wen-Feng Fang |
| author_facet | Chia-Cheng Tseng Chih-Yen Tu Chia-Hung Chen Yao-Tung Wang Wei-Chih Chen Pin-Kuei Fu Chin-Ming Chen Chih-Cheng Lai Li-Kuo Kuo Shih-Chi Ku Wen-Feng Fang |
| author_sort | Chia-Cheng Tseng |
| collection | DOAJ |
| description | Nutritional status could affect clinical outcomes in critical patients. We aimed to determine the prognostic accuracy of the modified Nutrition Risk in Critically Ill (mNUTRIC) score for hospital mortality and treatment outcomes in patients with severe community-acquired pneumonia (SCAP) compared to other clinical prediction rules. We enrolled SCAP patients in a multi-center setting retrospectively. The mNUTRIC score and clinical prediction rules for pneumonia, as well as clinical factors, were calculated and recorded. Clinical outcomes, including mortality status and treatment outcome, were assessed after the patient was discharged. We used the receiver operating characteristic (ROC) curve method and multivariate logistic regression analysis to determine the prognostic accuracy of the mNUTRIC score for predicting clinical outcomes compared to clinical prediction rules, while 815 SCAP patients were enrolled. ROC curve analysis showed that the mNUTRIC score was the most effective at predicting each clinical outcome and had the highest area under the ROC curve value. The cut-off value for predicting clinical outcomes was 5.5. By multivariate logistic regression analysis, the mNUTRIC score was also an independent predictor of both clinical outcomes in SCAP patients. We concluded that the mNUTRIC score is a better prognostic factor for predicting clinical outcomes in SCAP patients compared to other clinical prediction rules. |
| first_indexed | 2024-03-10T03:26:54Z |
| format | Article |
| id | doaj.art-4d2ecb9937c048a6ab20f13e6383cdec |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T03:26:54Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-4d2ecb9937c048a6ab20f13e6383cdec2023-11-23T12:05:43ZengMDPI AGNutrients2072-66432021-12-0114119810.3390/nu14010198Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired PneumoniaChia-Cheng Tseng0Chih-Yen Tu1Chia-Hung Chen2Yao-Tung Wang3Wei-Chih Chen4Pin-Kuei Fu5Chin-Ming Chen6Chih-Cheng Lai7Li-Kuo Kuo8Shih-Chi Ku9Wen-Feng Fang10Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung 404, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung 404, TaiwanDivision of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung 402, TaiwanDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei 11217, TaiwanDepartment of Critical Care Medicine, Taichung Veterans General Hospital, Taichung 407219, TaiwanDepartment of Intensive Care Medicine, Chi Mei Medical Centre, Tainan 710, TaiwanDepartment of Internal Medicine, Kaohsiung Veterans General Hospital, Tainan Branch, Tainan 71051, TaiwanDivision of Pulmonary and Critical Care Medicine, MacKay Memorial Hospital, Taipei 10449, TaiwanDivision of Chest Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 83301, TaiwanNutritional status could affect clinical outcomes in critical patients. We aimed to determine the prognostic accuracy of the modified Nutrition Risk in Critically Ill (mNUTRIC) score for hospital mortality and treatment outcomes in patients with severe community-acquired pneumonia (SCAP) compared to other clinical prediction rules. We enrolled SCAP patients in a multi-center setting retrospectively. The mNUTRIC score and clinical prediction rules for pneumonia, as well as clinical factors, were calculated and recorded. Clinical outcomes, including mortality status and treatment outcome, were assessed after the patient was discharged. We used the receiver operating characteristic (ROC) curve method and multivariate logistic regression analysis to determine the prognostic accuracy of the mNUTRIC score for predicting clinical outcomes compared to clinical prediction rules, while 815 SCAP patients were enrolled. ROC curve analysis showed that the mNUTRIC score was the most effective at predicting each clinical outcome and had the highest area under the ROC curve value. The cut-off value for predicting clinical outcomes was 5.5. By multivariate logistic regression analysis, the mNUTRIC score was also an independent predictor of both clinical outcomes in SCAP patients. We concluded that the mNUTRIC score is a better prognostic factor for predicting clinical outcomes in SCAP patients compared to other clinical prediction rules.https://www.mdpi.com/2072-6643/14/1/198nutritionsevere community-acquired pneumoniaclinical outcome |
| spellingShingle | Chia-Cheng Tseng Chih-Yen Tu Chia-Hung Chen Yao-Tung Wang Wei-Chih Chen Pin-Kuei Fu Chin-Ming Chen Chih-Cheng Lai Li-Kuo Kuo Shih-Chi Ku Wen-Feng Fang Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia Nutrients nutrition severe community-acquired pneumonia clinical outcome |
| title | Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia |
| title_full | Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia |
| title_fullStr | Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia |
| title_full_unstemmed | Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia |
| title_short | Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia |
| title_sort | significance of the modified nutric score for predicting clinical outcomes in patients with severe community acquired pneumonia |
| topic | nutrition severe community-acquired pneumonia clinical outcome |
| url | https://www.mdpi.com/2072-6643/14/1/198 |
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