Nicotine stimulates nerve growth factor in lung fibroblasts through an NFκB-dependent mechanism.

Nicotine stimulates nerve growth factor in lung fibroblasts through an NFκB-dependent mechanism.

Airway hyperresponsiveness (AHR) is classically found in asthma, and persistent AHR is associated with poor asthma control. Although airway smooth muscle (ASM) cells play a critical pathophysiologic role in AHR, the paracrine contributions of surrounding cells such as fibroblasts to the contractile...

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Bibliographic Details
Main Authors:	Cherry Wongtrakool, Kora Grooms, Kaiser M Bijli, Kristina Crothers, Anne M Fitzpatrick, C Michael Hart
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4190411?pdf=render

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