Late-Onset Calorie Restriction Improves Lipid Metabolism and Aggravates Inflammation in the Liver of Old Wistar Rats

Late-Onset Calorie Restriction Improves Lipid Metabolism and Aggravates Inflammation in the Liver of Old Wistar Rats

Aging is a progressive process that could disturb metabolic homeostasis in the liver via ectopic lipid accumulation, oxidative stress, and deterioration of inflammatory response. Although calorie restriction (CR) is recognized as beneficial for life span and health span prolongation, it is still unc...

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Bibliographic Details
Main Authors: Ana Teofilović, Miloš Vratarić, Nataša Veličković, Danijela Vojnović Milutinović, Aleksandra Mladenovic, Milica Prvulovic, Ana Djordjevic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Nutrition
Subjects:
calorie restriction
lipid metabolism
inflammation
liver
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.899255/full

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