Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine
Introduction: More than 500 million people throughout the world are infected with Toxoplasma gondii. On the other hand, migraine is known as the most common pain syndrome. The aim of this study was to detect anti-Toxoplasma gondii IgG in the serum of individuals with and without migraine. Methods: I...
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| Format: | Article |
| Language: | fas |
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Shahid Sadoughi University of Medical Sciences
2020-05-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| Subjects: | |
| Online Access: | http://jssu.ssu.ac.ir/article-1-4883-en.html |
| _version_ | 1828313017837682688 |
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| author | Niloufar Jouyani Mohammad Taghi Ahady Vahid Abbasi |
| author_facet | Niloufar Jouyani Mohammad Taghi Ahady Vahid Abbasi |
| author_sort | Niloufar Jouyani |
| collection | DOAJ |
| description | Introduction: More than 500 million people throughout the world are infected with Toxoplasma gondii. On the other hand, migraine is known as the most common pain syndrome. The aim of this study was to detect anti-Toxoplasma gondii IgG in the serum of individuals with and without migraine.
Methods: In this descriptive-analytical study, 50 person (7 male & 43 female, in the age range of 20-60 years) with history and symptoms of migraine (case group), and 50 individuals (7 male & 43 female, in the age range of 20-60 years) without migraine (control group) were selected randomly. Blood samples (5 ml) were collected from all the selected people, and the serum level of anti-Toxoplasma gondii IgG were determined using Enzyme-Linked Immunosorbent Assay (ELISA) technique. In this test, 10 IU/ml of anti-Toxoplasma gondii IgG was considered as the minimum titer. For statistical analysis SPSS Inc, Chicago, IL; Version 18 software and -Chi-square and t-tests were used.
Results: 38% of the patients with migraine and 32% of the control group had anti-Toxoplasma gondii IgG above 10 IU/ml. The mean amount of anti-T. gondii IgG in the serums of case group was 173.42 IU/ml, while it was 68.25 IU/ml in the control group, the mean amount of Toxo-IgG in migraine positive group was 2.5 time higher than the amount in the control group (p<0.05).
Conclusion: According to the results of this study it is concluded that the serum level of anti-Toxoplasma gondii IgG in migraine positive persons is significantly higher than the migraine negative individuals. Therefore, it is recommended that the patients disordered with migraine be tested for chronic toxoplasmosis.. |
| first_indexed | 2024-04-13T16:24:37Z |
| format | Article |
| id | doaj.art-4d35628eaf1446179a3ab334745a9baf |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-04-13T16:24:37Z |
| publishDate | 2020-05-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-4d35628eaf1446179a3ab334745a9baf2022-12-22T02:39:46ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332020-05-0128123152323Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without MigraineNiloufar Jouyani0Mohammad Taghi Ahady1Vahid Abbasi2 Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil Department of Neurology, Ardabil University of Medical Sciences, Ardabil Introduction: More than 500 million people throughout the world are infected with Toxoplasma gondii. On the other hand, migraine is known as the most common pain syndrome. The aim of this study was to detect anti-Toxoplasma gondii IgG in the serum of individuals with and without migraine. Methods: In this descriptive-analytical study, 50 person (7 male & 43 female, in the age range of 20-60 years) with history and symptoms of migraine (case group), and 50 individuals (7 male & 43 female, in the age range of 20-60 years) without migraine (control group) were selected randomly. Blood samples (5 ml) were collected from all the selected people, and the serum level of anti-Toxoplasma gondii IgG were determined using Enzyme-Linked Immunosorbent Assay (ELISA) technique. In this test, 10 IU/ml of anti-Toxoplasma gondii IgG was considered as the minimum titer. For statistical analysis SPSS Inc, Chicago, IL; Version 18 software and -Chi-square and t-tests were used. Results: 38% of the patients with migraine and 32% of the control group had anti-Toxoplasma gondii IgG above 10 IU/ml. The mean amount of anti-T. gondii IgG in the serums of case group was 173.42 IU/ml, while it was 68.25 IU/ml in the control group, the mean amount of Toxo-IgG in migraine positive group was 2.5 time higher than the amount in the control group (p<0.05). Conclusion: According to the results of this study it is concluded that the serum level of anti-Toxoplasma gondii IgG in migraine positive persons is significantly higher than the migraine negative individuals. Therefore, it is recommended that the patients disordered with migraine be tested for chronic toxoplasmosis..http://jssu.ssu.ac.ir/article-1-4883-en.htmlantibody iggtoxoplasma gondiichronic toxoplasmosismigraineelisa. |
| spellingShingle | Niloufar Jouyani Mohammad Taghi Ahady Vahid Abbasi Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd antibody igg toxoplasma gondii chronic toxoplasmosis migraine elisa. |
| title | Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine |
| title_full | Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine |
| title_fullStr | Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine |
| title_full_unstemmed | Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine |
| title_short | Serum Level of Anti-Toxoplasma Gondii IgG among the Individuals with/without Migraine |
| title_sort | serum level of anti toxoplasma gondii igg among the individuals with without migraine |
| topic | antibody igg toxoplasma gondii chronic toxoplasmosis migraine elisa. |
| url | http://jssu.ssu.ac.ir/article-1-4883-en.html |
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