Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging
This study aimed at evaluating the local tissue reaction of an anti-GnRF product, which is used for the so called “immunocastration” in male pigs. A total of 34 pigs were injected two times (including a booster injection) with an anti-GnRF product. Injection was performed using the prescribed safety...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/11/4/968 |
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| author | Maren Bernau Sebastian Schwanitz Lena Sophie Kreuzer Armin Manfred Scholz |
| author_facet | Maren Bernau Sebastian Schwanitz Lena Sophie Kreuzer Armin Manfred Scholz |
| author_sort | Maren Bernau |
| collection | DOAJ |
| description | This study aimed at evaluating the local tissue reaction of an anti-GnRF product, which is used for the so called “immunocastration” in male pigs. A total of 34 pigs were injected two times (including a booster injection) with an anti-GnRF product. Injection was performed using the prescribed safety vaccinator. Injection sites were evaluated three times post injection using magnetic resonance imaging. Two examinations were performed after the first injection and one after the booster. The local tissue reaction was evaluated three-dimensionally by semi-automatic analyses, by linear measurements of injection depth and length, and by scoring the kind of tissue affected. Results showed a long-lasting reaction in affected muscle tissue. Therefore, needle length should be discussed, and an evaluation of the injection site after slaughter should be performed include behavioural scorings post injection to evaluate the impact on animal well-being and carcass quality. |
| first_indexed | 2024-03-10T12:45:26Z |
| format | Article |
| id | doaj.art-4d363e9f65144bffb62b4c5eb3905a08 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T12:45:26Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-4d363e9f65144bffb62b4c5eb3905a082023-11-21T13:31:49ZengMDPI AGAnimals2076-26152021-03-0111496810.3390/ani11040968Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance ImagingMaren Bernau0Sebastian Schwanitz1Lena Sophie Kreuzer2Armin Manfred Scholz3Livestock Center Oberschleissheim, Veterinary Faculty of the Ludwig-Maximilians-University Munich, St. Hubertusstrasse 12, 85764 Oberschleissheim, GermanyLivestock Center Oberschleissheim, Veterinary Faculty of the Ludwig-Maximilians-University Munich, St. Hubertusstrasse 12, 85764 Oberschleissheim, GermanyLivestock Center Oberschleissheim, Veterinary Faculty of the Ludwig-Maximilians-University Munich, St. Hubertusstrasse 12, 85764 Oberschleissheim, GermanyLivestock Center Oberschleissheim, Veterinary Faculty of the Ludwig-Maximilians-University Munich, St. Hubertusstrasse 12, 85764 Oberschleissheim, GermanyThis study aimed at evaluating the local tissue reaction of an anti-GnRF product, which is used for the so called “immunocastration” in male pigs. A total of 34 pigs were injected two times (including a booster injection) with an anti-GnRF product. Injection was performed using the prescribed safety vaccinator. Injection sites were evaluated three times post injection using magnetic resonance imaging. Two examinations were performed after the first injection and one after the booster. The local tissue reaction was evaluated three-dimensionally by semi-automatic analyses, by linear measurements of injection depth and length, and by scoring the kind of tissue affected. Results showed a long-lasting reaction in affected muscle tissue. Therefore, needle length should be discussed, and an evaluation of the injection site after slaughter should be performed include behavioural scorings post injection to evaluate the impact on animal well-being and carcass quality.https://www.mdpi.com/2076-2615/11/4/968local reactionanti-GnRFpigsmagnetic resonance imaging |
| spellingShingle | Maren Bernau Sebastian Schwanitz Lena Sophie Kreuzer Armin Manfred Scholz Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging Animals local reaction anti-GnRF pigs magnetic resonance imaging |
| title | Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging |
| title_full | Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging |
| title_fullStr | Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging |
| title_full_unstemmed | Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging |
| title_short | Detection of Local Tissue Reactions after Anti-GnRF Injection in Male Pigs Assessed Using Magnetic Resonance Imaging |
| title_sort | detection of local tissue reactions after anti gnrf injection in male pigs assessed using magnetic resonance imaging |
| topic | local reaction anti-GnRF pigs magnetic resonance imaging |
| url | https://www.mdpi.com/2076-2615/11/4/968 |
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