Identification and validation of biomarkers related to lipid metabolism in osteoarthritis based on machine learning algorithms

Identification and validation of biomarkers related to lipid metabolism in osteoarthritis based on machine learning algorithms

Abstract Background Osteoarthritis and lipid metabolism are strongly associated, although the precise targets and regulatory mechanisms are unknown. Methods Osteoarthritis gene expression profiles were acquired from the GEO database, while lipid metabolism-related genes (LMRGs) were sourced from the...

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Bibliographic Details
Main Authors: Hang Li, Yubao Cui, Jian Wang, Wei Zhang, Yuhao Chen, Jijun Zhao
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Lipids in Health and Disease
Subjects:
Osteoarthritis
Lipid metabolism
Bioinformatics analysis
Hub genes
Machine learning
Immune infiltration
Online Access:https://doi.org/10.1186/s12944-024-02073-5

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