Light-Triggerable Liposomes for Enhanced Endolysosomal Escape and Gene Silencing in PC12 Cells

Light-Triggerable Liposomes for Enhanced Endolysosomal Escape and Gene Silencing in PC12 Cells

Liposomes are an effective gene and/or drug delivery system, widely used in biomedical applications including gene therapy and chemotherapy. Here, we designed a photo-responsive liposome (lipVP) loaded with a photosensitizer verteporfin (VP). This photosensitizer is clinically approved for photodyna...

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Bibliographic Details
Main Authors: Wenjie Chen, Wei Deng, Ewa M. Goldys
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
light-responsive
endosomal escape
liposomes
verteporfin
gene delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117301658

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