Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report
Abstract We report the first case of intraoperatively detected euglycemic diabetic ketoacidosis (DKA) associated with sodium–glucose cotransporter 2 inhibitors during thoracic surgery. A 59‐year‐old man had a 12‐year history of type 2 diabetes mellitus treated with insulin and empagliflozin. The pat...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-04-01
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| Series: | Journal of Diabetes Investigation |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jdi.13365 |
| _version_ | 1818652253694722048 |
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| author | Chie Kitahara Shuhei Morita Shohei Kishimoto Shohei Matsuno Shinsuke Uraki Ken Takeshima Yasushi Furukawa Hidefumi Inaba Hiroshi Iwakura Hiroyuki Ariyasu Hiroto Furuta Masahiro Nishi Takashi Akamizu |
| author_facet | Chie Kitahara Shuhei Morita Shohei Kishimoto Shohei Matsuno Shinsuke Uraki Ken Takeshima Yasushi Furukawa Hidefumi Inaba Hiroshi Iwakura Hiroyuki Ariyasu Hiroto Furuta Masahiro Nishi Takashi Akamizu |
| author_sort | Chie Kitahara |
| collection | DOAJ |
| description | Abstract We report the first case of intraoperatively detected euglycemic diabetic ketoacidosis (DKA) associated with sodium–glucose cotransporter 2 inhibitors during thoracic surgery. A 59‐year‐old man had a 12‐year history of type 2 diabetes mellitus treated with insulin and empagliflozin. The patient developed bacterial empyema and was initiated with antibiotics at a local hospital. Owing to the persistence of his symptoms, he was transferred to our hospital after the medication of empagliflozin the day before surgery. After overnight fasting, the patient underwent thoracoscopic debridement and intrathoracic lavage surgery. During this surgery, he was noted to have euglycemic ketosis and acidosis, and diagnosed as euglycemic DKA. Immediately after the consultation in our department, the patient underwent treatment for DKA. He awoke from anesthesia normally and showed no symptoms of DKA. DKA gradually resolved over the next 24 h. Early identification and management are critical for rapid recovery from perioperative euglycemic DKA associated with sodium–glucose cotransporter 2 inhibitors, especially during thoracic surgery. |
| first_indexed | 2024-12-17T02:19:04Z |
| format | Article |
| id | doaj.art-4d37dd9d30f14f198f73615bc4b38fa1 |
| institution | Directory Open Access Journal |
| issn | 2040-1116 2040-1124 |
| language | English |
| last_indexed | 2024-12-17T02:19:04Z |
| publishDate | 2021-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Investigation |
| spelling | doaj.art-4d37dd9d30f14f198f73615bc4b38fa12022-12-21T22:07:18ZengWileyJournal of Diabetes Investigation2040-11162040-11242021-04-0112466466710.1111/jdi.13365Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case reportChie Kitahara0Shuhei Morita1Shohei Kishimoto2Shohei Matsuno3Shinsuke Uraki4Ken Takeshima5Yasushi Furukawa6Hidefumi Inaba7Hiroshi Iwakura8Hiroyuki Ariyasu9Hiroto Furuta10Masahiro Nishi11Takashi Akamizu12The First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanThe First Department of Medicine Wakayama Medical University Wakayama JapanAbstract We report the first case of intraoperatively detected euglycemic diabetic ketoacidosis (DKA) associated with sodium–glucose cotransporter 2 inhibitors during thoracic surgery. A 59‐year‐old man had a 12‐year history of type 2 diabetes mellitus treated with insulin and empagliflozin. The patient developed bacterial empyema and was initiated with antibiotics at a local hospital. Owing to the persistence of his symptoms, he was transferred to our hospital after the medication of empagliflozin the day before surgery. After overnight fasting, the patient underwent thoracoscopic debridement and intrathoracic lavage surgery. During this surgery, he was noted to have euglycemic ketosis and acidosis, and diagnosed as euglycemic DKA. Immediately after the consultation in our department, the patient underwent treatment for DKA. He awoke from anesthesia normally and showed no symptoms of DKA. DKA gradually resolved over the next 24 h. Early identification and management are critical for rapid recovery from perioperative euglycemic DKA associated with sodium–glucose cotransporter 2 inhibitors, especially during thoracic surgery.https://doi.org/10.1111/jdi.13365EmpagliflozinIntraoperative euglycemic ketoacidosisSodium–glucose cotransporter 2 inhibitor |
| spellingShingle | Chie Kitahara Shuhei Morita Shohei Kishimoto Shohei Matsuno Shinsuke Uraki Ken Takeshima Yasushi Furukawa Hidefumi Inaba Hiroshi Iwakura Hiroyuki Ariyasu Hiroto Furuta Masahiro Nishi Takashi Akamizu Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report Journal of Diabetes Investigation Empagliflozin Intraoperative euglycemic ketoacidosis Sodium–glucose cotransporter 2 inhibitor |
| title | Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report |
| title_full | Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report |
| title_fullStr | Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report |
| title_full_unstemmed | Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report |
| title_short | Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report |
| title_sort | early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes a case report |
| topic | Empagliflozin Intraoperative euglycemic ketoacidosis Sodium–glucose cotransporter 2 inhibitor |
| url | https://doi.org/10.1111/jdi.13365 |
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