DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
Abstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/233 |
| _version_ | 1797198083983933440 |
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| author | T. I. Dolgikh V. I. Sovalkin I. V. Menshchikova |
| author_facet | T. I. Dolgikh V. I. Sovalkin I. V. Menshchikova |
| author_sort | T. I. Dolgikh |
| collection | DOAJ |
| description | Abstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients, isolation of bacterial microflora was associated with positive antibody titers to Mycoplasma pneumoniae. Serum contents of cytokines (TNFα, IL-8, IL-6) have been studied in the patients. A positive correlation was found between increased cytokine levels and severity of the disease. |
| first_indexed | 2024-03-08T05:51:30Z |
| format | Article |
| id | doaj.art-4d39a71439684691a2aacd00e58d8969 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:54:14Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-4d39a71439684691a2aacd00e58d89692024-04-22T13:07:34ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0194-551952210.15789/1563-0625-2007-4-5-519-522230DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAST. I. Dolgikh0V. I. Sovalkin1I. V. Menshchikova2Омская государственная медицинская академияОмская государственная медицинская академияОбластная клиническая больница, г. ОмскAbstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients, isolation of bacterial microflora was associated with positive antibody titers to Mycoplasma pneumoniae. Serum contents of cytokines (TNFα, IL-8, IL-6) have been studied in the patients. A positive correlation was found between increased cytokine levels and severity of the disease.https://www.mimmun.ru/mimmun/article/view/233pneumoniam. pneumoniaecytokinesimmunitytnfαil-8il-6 |
| spellingShingle | T. I. Dolgikh V. I. Sovalkin I. V. Menshchikova DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS Медицинская иммунология pneumonia m. pneumoniae cytokines immunity tnfα il-8 il-6 |
| title | DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS |
| title_full | DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS |
| title_fullStr | DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS |
| title_full_unstemmed | DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS |
| title_short | DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS |
| title_sort | diagnostic and predictive value of tnf α il 8 and il 6 assays in the patients with mycoplasma associated pneumonias |
| topic | pneumonia m. pneumoniae cytokines immunity tnfα il-8 il-6 |
| url | https://www.mimmun.ru/mimmun/article/view/233 |
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