Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit

A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side e...

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Main Authors: Fayeza Mohammed, Laura L. Wally, Jeffrey E. Karaban, Vijaya B. Reddy, Yongsuk Lertratanakul
Format: Article
Language:English
Published: Karger Publishers 2017-11-01
Series:Case Reports in Dermatology
Subjects:
Online Access:https://www.karger.com/Article/FullText/484471
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author Fayeza Mohammed
Laura L. Wally
Jeffrey E. Karaban
Vijaya B. Reddy
Yongsuk Lertratanakul
author_facet Fayeza Mohammed
Laura L. Wally
Jeffrey E. Karaban
Vijaya B. Reddy
Yongsuk Lertratanakul
author_sort Fayeza Mohammed
collection DOAJ
description A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side effect of fenofibrate. In addition, we report a potential familial association which underscores the potential for underlying genetic mechanisms to be contributory to lichenoid drug eruptions. A reminder of the physical characteristics of lichen planus, knowledge of the temporal relation between administration of medications and a lichenoid drug eruption, recognition of the effect of UV exposure on lichenoid drug eruptions, and realization for the potential of symptoms to persist despite discontinuation of an offending agent can aid practitioners in promptly diagnosing lichenoid drug eruptions and initiating appropriate therapy.
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spelling doaj.art-4d3e45b735434001a5592ad7c8534efc2022-12-22T03:22:44ZengKarger PublishersCase Reports in Dermatology1662-65672017-11-019323624210.1159/000484471484471Fenofibrate-Induced Lichenoid Drug Eruption: A Rare CulpritFayeza MohammedLaura L. WallyJeffrey E. KarabanVijaya B. ReddyYongsuk LertratanakulA lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side effect of fenofibrate. In addition, we report a potential familial association which underscores the potential for underlying genetic mechanisms to be contributory to lichenoid drug eruptions. A reminder of the physical characteristics of lichen planus, knowledge of the temporal relation between administration of medications and a lichenoid drug eruption, recognition of the effect of UV exposure on lichenoid drug eruptions, and realization for the potential of symptoms to persist despite discontinuation of an offending agent can aid practitioners in promptly diagnosing lichenoid drug eruptions and initiating appropriate therapy.https://www.karger.com/Article/FullText/484471LichenoidRashDrug eruptionFenofibratePhotosensitivity
spellingShingle Fayeza Mohammed
Laura L. Wally
Jeffrey E. Karaban
Vijaya B. Reddy
Yongsuk Lertratanakul
Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
Case Reports in Dermatology
Lichenoid
Rash
Drug eruption
Fenofibrate
Photosensitivity
title Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_full Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_fullStr Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_full_unstemmed Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_short Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_sort fenofibrate induced lichenoid drug eruption a rare culprit
topic Lichenoid
Rash
Drug eruption
Fenofibrate
Photosensitivity
url https://www.karger.com/Article/FullText/484471
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AT lauralwally fenofibrateinducedlichenoiddrugeruptionarareculprit
AT jeffreyekaraban fenofibrateinducedlichenoiddrugeruptionarareculprit
AT vijayabreddy fenofibrateinducedlichenoiddrugeruptionarareculprit
AT yongsuklertratanakul fenofibrateinducedlichenoiddrugeruptionarareculprit