CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING
Objective – to study the advantages of liquid-based cytology in comparison with Pap test in early diagnosis of cervical cancer. Materials and methods. The clinical records of 145 women of reproductive age were analysed. The women had applied to antenatal clinic in Clinical Policlinic N 20 were studi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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The Publishing House Medicine and Enlightenment
2019-10-01
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| Series: | Мать и дитя в Кузбассе |
| Subjects: | |
| Online Access: | http://mednauki.ru/index.php/MD/article/view/386 |
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| author | Светлана Ивановна Елгина Ольга Сергеевна Золоторевская Игорь Сергеевич Захаров Вадим Гельевич Мозес Елена Владимировна Рудаева Виктория Анатольевна Разумова Алексей Юрьевич Кратовский |
| author_facet | Светлана Ивановна Елгина Ольга Сергеевна Золоторевская Игорь Сергеевич Захаров Вадим Гельевич Мозес Елена Владимировна Рудаева Виктория Анатольевна Разумова Алексей Юрьевич Кратовский |
| author_sort | Светлана Ивановна Елгина |
| collection | DOAJ |
| description | Objective – to study the advantages of liquid-based cytology in comparison with Pap test in early diagnosis of cervical cancer.
Materials and methods. The clinical records of 145 women of reproductive age were analysed. The women had applied to antenatal clinic in Clinical Policlinic N 20 were studied by clinical, laboratory, statistical methods. All women underwent cytological screening both with a technology such as the PAP test and a liquid-based one.
Results. While estimating sensitivity, specificity and prognostic value of the cytological screening, the following findings were received: The sensitivity of liquid-based cytology was 70.0 % while that of the Pap test – 60.0 %. The specificity of liquid-based cytology (86.0 %) was lower than that of the PAP test (88.0 %). The prognostic value of the positive result of the liquid-based cytology test (75.0 %) was identical to the PAP test (87.0 %) prognostic value. However, the prognostic value of the negative result of the liquid-based cytology test (83.0 %) was much higher than that of the PAP test (50.0 %).
Conclusion: We identified that both screenings have similar prediction value for disease probability. However liquid-based cytology test allows reducing the number of negative results. Currently a wide application of more efficient methods – detection of Human Papilloma Virus DNA of high oncogenic risk – is required for the well-arranged screening program. |
| first_indexed | 2024-12-10T18:29:08Z |
| format | Article |
| id | doaj.art-4d41017d69e74720811eddf97b8891bb |
| institution | Directory Open Access Journal |
| issn | 1991-010X 2542-0968 |
| language | Russian |
| last_indexed | 2024-12-10T18:29:08Z |
| publishDate | 2019-10-01 |
| publisher | The Publishing House Medicine and Enlightenment |
| record_format | Article |
| series | Мать и дитя в Кузбассе |
| spelling | doaj.art-4d41017d69e74720811eddf97b8891bb2022-12-22T01:37:59ZrusThe Publishing House Medicine and EnlightenmentМать и дитя в Кузбассе1991-010X2542-09682019-10-012033740346CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSINGСветлана Ивановна Елгина0Ольга Сергеевна Золоторевская1Игорь Сергеевич Захаров2Вадим Гельевич Мозес3Елена Владимировна Рудаева4Виктория Анатольевна Разумова5Алексей Юрьевич Кратовский6ФГБОУ ВО КемГМУ Минздрава России, г. КемеровоГБУЗ КО КГКП № 20», г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоObjective – to study the advantages of liquid-based cytology in comparison with Pap test in early diagnosis of cervical cancer. Materials and methods. The clinical records of 145 women of reproductive age were analysed. The women had applied to antenatal clinic in Clinical Policlinic N 20 were studied by clinical, laboratory, statistical methods. All women underwent cytological screening both with a technology such as the PAP test and a liquid-based one. Results. While estimating sensitivity, specificity and prognostic value of the cytological screening, the following findings were received: The sensitivity of liquid-based cytology was 70.0 % while that of the Pap test – 60.0 %. The specificity of liquid-based cytology (86.0 %) was lower than that of the PAP test (88.0 %). The prognostic value of the positive result of the liquid-based cytology test (75.0 %) was identical to the PAP test (87.0 %) prognostic value. However, the prognostic value of the negative result of the liquid-based cytology test (83.0 %) was much higher than that of the PAP test (50.0 %). Conclusion: We identified that both screenings have similar prediction value for disease probability. However liquid-based cytology test allows reducing the number of negative results. Currently a wide application of more efficient methods – detection of Human Papilloma Virus DNA of high oncogenic risk – is required for the well-arranged screening program.http://mednauki.ru/index.php/MD/article/view/386женщиныцитологический скрининг путем пап- теста и жидкостный |
| spellingShingle | Светлана Ивановна Елгина Ольга Сергеевна Золоторевская Игорь Сергеевич Захаров Вадим Гельевич Мозес Елена Владимировна Рудаева Виктория Анатольевна Разумова Алексей Юрьевич Кратовский CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING Мать и дитя в Кузбассе женщины цитологический скрининг путем пап- теста и жидкостный |
| title | CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING |
| title_full | CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING |
| title_fullStr | CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING |
| title_full_unstemmed | CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING |
| title_short | CYTOLOGICAL SCREENING FOR CERVICAL CANCER DIAGNOSING |
| title_sort | cytological screening for cervical cancer diagnosing |
| topic | женщины цитологический скрининг путем пап- теста и жидкостный |
| url | http://mednauki.ru/index.php/MD/article/view/386 |
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