Use of Artemisinin- Combination Therapies in Port Harcourt

Malaria still constitutes a public health problem in Nigeria and it is the leading cause of morbidity and mortality in Sub –Saharan Africa. The emergence and spread of Plasmodium falciparum parasite resistance to commonly used antimalarials such as chloroquine and  sulphadoxine/pyrimethamine has po...

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Main Authors: OA Shorinwa, OO Ebong
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2013-07-01
Series:Journal of Applied Sciences and Environmental Management
Online Access:https://www.ajol.info/index.php/jasem/article/view/90776
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author OA Shorinwa
OO Ebong
author_facet OA Shorinwa
OO Ebong
author_sort OA Shorinwa
collection DOAJ
description Malaria still constitutes a public health problem in Nigeria and it is the leading cause of morbidity and mortality in Sub –Saharan Africa. The emergence and spread of Plasmodium falciparum parasite resistance to commonly used antimalarials such as chloroquine and  sulphadoxine/pyrimethamine has posed challenges to malaria control. The World Health Organization (WHO) recommends the use of Artemisinin- based combination therapies (ACTs) as the first line of treatment for malaria in Sub –Saharan Africa. This study was carried out to determine the pattern of use of ACTs in Port Harcourt so as to identify problems associated with ACTS use and to contribute to malaria control programme in the country. The parameters investigated include the demography, frequency of malaria attacks, place of treatment, mode of treatment and specific antimalarial drug treatment. A survey was conducted with the aid of structured questionnaires in Port Harcourt metropolis. Of the 717 questionnaires that were returned and evaluated, 690 (96.2%) respondents claimed to have had malaria within the last one year; 244 (34%) received treatment from hospitals; 273 (38.1%) received treatment from pharmacies; 137 (19.1%) engaged in self medication and 17 (2.4%) received herbal treatment. The respondents that took artemisinin based combination drugs were 230 (32.1%), those that took artesunate only were 174 (24.3%), those that took chloroquine were 101 (14.1%) while those that took sulphadoxine/pyrimethamine were 140 (19.5%) while 72 (10%) took other antimalarial drugs. This study suggests that a majority of respondents in the study area take ACTs for the treatment of malaria. @JASEM Keywords: Artemisinin-based combination therapy (ACT), Malaria, Antimalarial
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spelling doaj.art-4d4fbc22a923479e84300cc4664831042024-04-22T19:46:45ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992013-07-01161Use of Artemisinin- Combination Therapies in Port HarcourtOA ShorinwaOO Ebong Malaria still constitutes a public health problem in Nigeria and it is the leading cause of morbidity and mortality in Sub –Saharan Africa. The emergence and spread of Plasmodium falciparum parasite resistance to commonly used antimalarials such as chloroquine and  sulphadoxine/pyrimethamine has posed challenges to malaria control. The World Health Organization (WHO) recommends the use of Artemisinin- based combination therapies (ACTs) as the first line of treatment for malaria in Sub –Saharan Africa. This study was carried out to determine the pattern of use of ACTs in Port Harcourt so as to identify problems associated with ACTS use and to contribute to malaria control programme in the country. The parameters investigated include the demography, frequency of malaria attacks, place of treatment, mode of treatment and specific antimalarial drug treatment. A survey was conducted with the aid of structured questionnaires in Port Harcourt metropolis. Of the 717 questionnaires that were returned and evaluated, 690 (96.2%) respondents claimed to have had malaria within the last one year; 244 (34%) received treatment from hospitals; 273 (38.1%) received treatment from pharmacies; 137 (19.1%) engaged in self medication and 17 (2.4%) received herbal treatment. The respondents that took artemisinin based combination drugs were 230 (32.1%), those that took artesunate only were 174 (24.3%), those that took chloroquine were 101 (14.1%) while those that took sulphadoxine/pyrimethamine were 140 (19.5%) while 72 (10%) took other antimalarial drugs. This study suggests that a majority of respondents in the study area take ACTs for the treatment of malaria. @JASEM Keywords: Artemisinin-based combination therapy (ACT), Malaria, Antimalarial https://www.ajol.info/index.php/jasem/article/view/90776
spellingShingle OA Shorinwa
OO Ebong
Use of Artemisinin- Combination Therapies in Port Harcourt
Journal of Applied Sciences and Environmental Management
title Use of Artemisinin- Combination Therapies in Port Harcourt
title_full Use of Artemisinin- Combination Therapies in Port Harcourt
title_fullStr Use of Artemisinin- Combination Therapies in Port Harcourt
title_full_unstemmed Use of Artemisinin- Combination Therapies in Port Harcourt
title_short Use of Artemisinin- Combination Therapies in Port Harcourt
title_sort use of artemisinin combination therapies in port harcourt
url https://www.ajol.info/index.php/jasem/article/view/90776
work_keys_str_mv AT oashorinwa useofartemisinincombinationtherapiesinportharcourt
AT ooebong useofartemisinincombinationtherapiesinportharcourt