Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment
Owing to high efficacy and safety, natural medicines have found their way into the field of cancer therapy over the past few decades. However, the effective ingredients of natural medicines have shortcomings of poor solubility and low bioavailability. Nanoparticles can not only solve the problems ab...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/23/7767 |
| _version_ | 1797399834038108160 |
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| author | Yu Hu Jizheng Song Anjie Feng Jieyu Li Mengqi Li Yu Shi Wenxiu Sun Lingjun Li |
| author_facet | Yu Hu Jizheng Song Anjie Feng Jieyu Li Mengqi Li Yu Shi Wenxiu Sun Lingjun Li |
| author_sort | Yu Hu |
| collection | DOAJ |
| description | Owing to high efficacy and safety, natural medicines have found their way into the field of cancer therapy over the past few decades. However, the effective ingredients of natural medicines have shortcomings of poor solubility and low bioavailability. Nanoparticles can not only solve the problems above but also have outstanding targeting ability. Targeting preparations can be classified into three levels, which are target tissues, cells, and organelles. On the premise of clarifying the therapeutic purpose of drugs, one or more targeting methods can be selected to achieve more accurate drug delivery and consequently to improve the anti-tumor effects of drugs and reduce toxicity and side effects. The aim of this review is to summarize the research status of natural medicines’ nano-preparations in tumor-targeting therapies to provide some references for further accurate and effective cancer treatments. |
| first_indexed | 2024-03-09T01:45:51Z |
| format | Article |
| id | doaj.art-4d527c7b88d04eb484bfd3b72504c5f9 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T01:45:51Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-4d527c7b88d04eb484bfd3b72504c5f92023-12-08T15:22:17ZengMDPI AGMolecules1420-30492023-11-012823776710.3390/molecules28237767Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer TreatmentYu Hu0Jizheng Song1Anjie Feng2Jieyu Li3Mengqi Li4Yu Shi5Wenxiu Sun6Lingjun Li7School of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaSchool of Pharmacy, Shandong University of Traditional Chinese Medicine (TCM), Jinan 250355, ChinaOwing to high efficacy and safety, natural medicines have found their way into the field of cancer therapy over the past few decades. However, the effective ingredients of natural medicines have shortcomings of poor solubility and low bioavailability. Nanoparticles can not only solve the problems above but also have outstanding targeting ability. Targeting preparations can be classified into three levels, which are target tissues, cells, and organelles. On the premise of clarifying the therapeutic purpose of drugs, one or more targeting methods can be selected to achieve more accurate drug delivery and consequently to improve the anti-tumor effects of drugs and reduce toxicity and side effects. The aim of this review is to summarize the research status of natural medicines’ nano-preparations in tumor-targeting therapies to provide some references for further accurate and effective cancer treatments.https://www.mdpi.com/1420-3049/28/23/7767nanoparticlestumor targetingnatural medicines |
| spellingShingle | Yu Hu Jizheng Song Anjie Feng Jieyu Li Mengqi Li Yu Shi Wenxiu Sun Lingjun Li Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment Molecules nanoparticles tumor targeting natural medicines |
| title | Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment |
| title_full | Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment |
| title_fullStr | Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment |
| title_full_unstemmed | Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment |
| title_short | Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment |
| title_sort | recent advances in nanotechnology based targeted delivery systems of active constituents in natural medicines for cancer treatment |
| topic | nanoparticles tumor targeting natural medicines |
| url | https://www.mdpi.com/1420-3049/28/23/7767 |
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