Vaccine rollout strategies: The case for vaccinating essential workers early.

In vaccination campaigns against COVID-19, many jurisdictions are using age-based rollout strategies, reflecting the much higher risk of severe outcomes of infection in older groups. In the wake of growing evidence that approved vaccines are effective at preventing not only adverse outcomes, but als...

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Main Authors: Nicola Mulberry, Paul Tupper, Erin Kirwin, Christopher McCabe, Caroline Colijn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLOS Global Public Health
Online Access:https://doi.org/10.1371/journal.pgph.0000020
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author Nicola Mulberry
Paul Tupper
Erin Kirwin
Christopher McCabe
Caroline Colijn
author_facet Nicola Mulberry
Paul Tupper
Erin Kirwin
Christopher McCabe
Caroline Colijn
author_sort Nicola Mulberry
collection DOAJ
description In vaccination campaigns against COVID-19, many jurisdictions are using age-based rollout strategies, reflecting the much higher risk of severe outcomes of infection in older groups. In the wake of growing evidence that approved vaccines are effective at preventing not only adverse outcomes, but also infection, we show that such strategies are less effective than strategies that prioritize essential workers. This conclusion holds across numerous outcomes, including cases, hospitalizations, Long COVID (cases with symptoms lasting longer than 28 days), deaths and net monetary benefit. Our analysis holds in regions where the vaccine supply is limited, and rollout is prolonged for several months. In such a setting with a population of 5M, we estimate that vaccinating essential workers sooner prevents over 200,000 infections, over 600 deaths, and produces a net monetary benefit of over $500M.
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spelling doaj.art-4d554a394ed64c63a00e7c5bbcb4d5582023-09-03T13:26:21ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752021-01-01110e000002010.1371/journal.pgph.0000020Vaccine rollout strategies: The case for vaccinating essential workers early.Nicola MulberryPaul TupperErin KirwinChristopher McCabeCaroline ColijnIn vaccination campaigns against COVID-19, many jurisdictions are using age-based rollout strategies, reflecting the much higher risk of severe outcomes of infection in older groups. In the wake of growing evidence that approved vaccines are effective at preventing not only adverse outcomes, but also infection, we show that such strategies are less effective than strategies that prioritize essential workers. This conclusion holds across numerous outcomes, including cases, hospitalizations, Long COVID (cases with symptoms lasting longer than 28 days), deaths and net monetary benefit. Our analysis holds in regions where the vaccine supply is limited, and rollout is prolonged for several months. In such a setting with a population of 5M, we estimate that vaccinating essential workers sooner prevents over 200,000 infections, over 600 deaths, and produces a net monetary benefit of over $500M.https://doi.org/10.1371/journal.pgph.0000020
spellingShingle Nicola Mulberry
Paul Tupper
Erin Kirwin
Christopher McCabe
Caroline Colijn
Vaccine rollout strategies: The case for vaccinating essential workers early.
PLOS Global Public Health
title Vaccine rollout strategies: The case for vaccinating essential workers early.
title_full Vaccine rollout strategies: The case for vaccinating essential workers early.
title_fullStr Vaccine rollout strategies: The case for vaccinating essential workers early.
title_full_unstemmed Vaccine rollout strategies: The case for vaccinating essential workers early.
title_short Vaccine rollout strategies: The case for vaccinating essential workers early.
title_sort vaccine rollout strategies the case for vaccinating essential workers early
url https://doi.org/10.1371/journal.pgph.0000020
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