Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4+ T Cells via Pneumolysin

Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4+ T Cells via Pneumolysin

Influenza A Virus (IAV), Staphylococcus aureus (staphylococci), and Streptococcus pneumoniae (pneumococci) are leading viral and bacterial causes of pneumonia. Dendritic cells (DCs) are present in the lower respiratory tract. They are characterized by low expression of co-stimulatory molecules, incl...

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Bibliographic Details
Main Authors: Antje D. Paulikat, Lea A. Tölken, Lana H. Jachmann, Gerhard Burchhardt, Sven Hammerschmidt, Nikolai Siemens
Format: Article
Language:English
Published: Karger Publishers 2022-03-01
Series:Journal of Innate Immunity
Subjects:
dendritic cells
streptococcus pneumoniae
staphylococcus aureus
influenza a virus
pneumolysin
Online Access:https://www.karger.com/Article/FullText/522339

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