Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice
This study theoretically demonstrated an insight for designing a novel tunable plasmonic biosensor, which was created by simply stacking a twisted bilayer graphene (TBG) superlattice onto a plasmonic gold thin film. To achieve ultrasensitive biosensing, the plasmonic biosensor was modulated by Goos–...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-03-01
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| Series: | Nanophotonics |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/nanoph-2022-0798 |
| _version_ | 1827969037942915072 |
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| author | Du Fusheng Zheng Kai Zeng Shuwen Yuan Yufeng |
| author_facet | Du Fusheng Zheng Kai Zeng Shuwen Yuan Yufeng |
| author_sort | Du Fusheng |
| collection | DOAJ |
| description | This study theoretically demonstrated an insight for designing a novel tunable plasmonic biosensor, which was created by simply stacking a twisted bilayer graphene (TBG) superlattice onto a plasmonic gold thin film. To achieve ultrasensitive biosensing, the plasmonic biosensor was modulated by Goos–Hänchen (GH) shift. Interestingly, our proposed biosensor exhibited tunable biosensing ability, largely depending on the twisted angle. When the relative twisted angle was optimized to be 55.3°, such a configuration: 44 nm Au film/1-TBG superlattice could produce an ultralow reflectivity of 2.2038 × 10−9 and ultra-large GH shift of 4.4785 × 104 µm. For a small refractive index (RI) increment of 0.0012 RIU (refractive index unit) in sensing interface, the optimal configuration could offer an ultra-high GH shift detection sensitivity of 3.9570 × 107 µm/RIU. More importantly, the optimal plasmonic configuration demonstrated a theoretical possibility of quantitatively monitoring severe acute respiratory syndrome coronavirus (SARS-CoV-2) and human hemoglobin. Considering an extremely small RI change as little as 3 × 10−7 RIU, a good linear response between detection concentration of SARS-CoV-2 and changes in differential GH shift was studied. For SARS-CoV-2, a linear detection interval was obtained from 0 to 2 nM. For human hemoglobin, a linear detection range was achieved from 0 to 0.002 g/L. Our work will be important to develop novel TBG-enhanced biosensors for quantitatively detecting microorganisms and biomolecules in biomedical application. |
| first_indexed | 2024-04-09T18:30:45Z |
| format | Article |
| id | doaj.art-4d5feab512774a2f80eda9b218fcbf5e |
| institution | Directory Open Access Journal |
| issn | 2192-8614 |
| language | English |
| last_indexed | 2024-04-09T18:30:45Z |
| publishDate | 2023-03-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Nanophotonics |
| spelling | doaj.art-4d5feab512774a2f80eda9b218fcbf5e2023-04-11T17:07:18ZengDe GruyterNanophotonics2192-86142023-03-011271271128410.1515/nanoph-2022-0798Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlatticeDu Fusheng0Zheng Kai1Zeng Shuwen2Yuan Yufeng3School of Electronic Engineering and Intelligentization, Dongguan University of Technology, Dongguan, 523808, ChinaSchool of Civil Aviation, Northwestern Polytechnical University, Xi’an, Shanxi, 710072, ChinaLight, Nanomaterials & Nanotechnologies (L2n), CNRS-ERL 7004, Université de Technologie de Troyes, Troyes, 10000, FranceSchool of Electronic Engineering and Intelligentization, Dongguan University of Technology, Dongguan, 523808, ChinaThis study theoretically demonstrated an insight for designing a novel tunable plasmonic biosensor, which was created by simply stacking a twisted bilayer graphene (TBG) superlattice onto a plasmonic gold thin film. To achieve ultrasensitive biosensing, the plasmonic biosensor was modulated by Goos–Hänchen (GH) shift. Interestingly, our proposed biosensor exhibited tunable biosensing ability, largely depending on the twisted angle. When the relative twisted angle was optimized to be 55.3°, such a configuration: 44 nm Au film/1-TBG superlattice could produce an ultralow reflectivity of 2.2038 × 10−9 and ultra-large GH shift of 4.4785 × 104 µm. For a small refractive index (RI) increment of 0.0012 RIU (refractive index unit) in sensing interface, the optimal configuration could offer an ultra-high GH shift detection sensitivity of 3.9570 × 107 µm/RIU. More importantly, the optimal plasmonic configuration demonstrated a theoretical possibility of quantitatively monitoring severe acute respiratory syndrome coronavirus (SARS-CoV-2) and human hemoglobin. Considering an extremely small RI change as little as 3 × 10−7 RIU, a good linear response between detection concentration of SARS-CoV-2 and changes in differential GH shift was studied. For SARS-CoV-2, a linear detection interval was obtained from 0 to 2 nM. For human hemoglobin, a linear detection range was achieved from 0 to 0.002 g/L. Our work will be important to develop novel TBG-enhanced biosensors for quantitatively detecting microorganisms and biomolecules in biomedical application.https://doi.org/10.1515/nanoph-2022-0798gh shifthuman hemoglobinsars-cov-2sensitivity enhancementtunable plasmonic biosensortwisted bilayer graphene superlattice |
| spellingShingle | Du Fusheng Zheng Kai Zeng Shuwen Yuan Yufeng Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice Nanophotonics gh shift human hemoglobin sars-cov-2 sensitivity enhancement tunable plasmonic biosensor twisted bilayer graphene superlattice |
| title | Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice |
| title_full | Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice |
| title_fullStr | Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice |
| title_full_unstemmed | Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice |
| title_short | Sensitivity enhanced tunable plasmonic biosensor using two-dimensional twisted bilayer graphene superlattice |
| title_sort | sensitivity enhanced tunable plasmonic biosensor using two dimensional twisted bilayer graphene superlattice |
| topic | gh shift human hemoglobin sars-cov-2 sensitivity enhancement tunable plasmonic biosensor twisted bilayer graphene superlattice |
| url | https://doi.org/10.1515/nanoph-2022-0798 |
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