Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics

Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics

BackgroundSpatial transcriptomics (STs) simultaneously obtains the location and amount of gene expression within a tissue section. However, current methods like FindMarkers calculated the differentially expressed genes (DEGs) based on the classical statistics, which should abolish the spatial inform...

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Bibliographic Details
Main Authors:	Zhihua Qiu, Shaojun Li, Ming Luo, Shuanggen Zhu, Zhijian Wang, Yongjun Jiang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Neuroscience
Subjects:	spatial transcriptomics DEGs spatial statistics saSpatial stroke
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2022.1086168/full

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