Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China.
<h4>Background</h4>The aim of this study was to test the ability of the Chinese version of the Mood Disorder Questionnaire (MDQ) to identify Bipolar Disorders (BD) in patients diagnosed with Major Depressive Disorder (MDD) or Unipolar Disorder (UD) in the clinical setting.<h4>Metho...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0091895&type=printable |
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| author | Hai-Chen Yang Tie-Bang Liu Han Rong Jian-Qiang Bi Er-Ni Ji Hong-Jun Peng Xiao-Ping Wang Yi-Ru Fang Cheng-Mei Yuan Tian-Mei Si Zheng Lu Jian Hu Zhi-Yu Chen Yi Huang Jing Sun Hui-Chun Li Chen Hu Jin-Bei Zhang Ling-Jiang Li |
| author_facet | Hai-Chen Yang Tie-Bang Liu Han Rong Jian-Qiang Bi Er-Ni Ji Hong-Jun Peng Xiao-Ping Wang Yi-Ru Fang Cheng-Mei Yuan Tian-Mei Si Zheng Lu Jian Hu Zhi-Yu Chen Yi Huang Jing Sun Hui-Chun Li Chen Hu Jin-Bei Zhang Ling-Jiang Li |
| author_sort | Hai-Chen Yang |
| collection | DOAJ |
| description | <h4>Background</h4>The aim of this study was to test the ability of the Chinese version of the Mood Disorder Questionnaire (MDQ) to identify Bipolar Disorders (BD) in patients diagnosed with Major Depressive Disorder (MDD) or Unipolar Disorder (UD) in the clinical setting.<h4>Methods</h4>1,487 being treated for MDD or UD at 12 mental health centers across China, completed the MDQ and subsequently examined by the Mini International Neuropsychiatric Interview (MINI). Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II.<h4>Results</h4>Of the 1,487 patients, 309 (20.8%) satisfied the DSM-IV criteria for BD: 118 (7.9%) for BD-I and 191 (12.8%) for BD-II. When only part one of the MDQ was used, the best cutoff was 7 between BD and UD (sensitivity 0.66, specificity 0.88, positive predictive value 0.59, negative predictive value 0.91), 6 between BD-II and UD, and 10 between BD-I and BD-II. If all three parts of the MDQ were used, the MDQ could not distinguish between BD and UD at a cutoff of 7 (or 6), and the sensitivity was only 0.22 (or 0.24).<h4>Conclusion</h4>The Chinese version of the MDQ had good psychometric features in screening bipolar disorders from depressive patients with mood disorders when part two and part three of the MDQ were ignored. |
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| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2025-03-17T00:32:23Z |
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| spelling | doaj.art-4d6ae708ae764bc0b0f47869aa5b81282025-02-21T05:34:52ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9189510.1371/journal.pone.0091895Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China.Hai-Chen YangTie-Bang LiuHan RongJian-Qiang BiEr-Ni JiHong-Jun PengXiao-Ping WangYi-Ru FangCheng-Mei YuanTian-Mei SiZheng LuJian HuZhi-Yu ChenYi HuangJing SunHui-Chun LiChen HuJin-Bei ZhangLing-Jiang Li<h4>Background</h4>The aim of this study was to test the ability of the Chinese version of the Mood Disorder Questionnaire (MDQ) to identify Bipolar Disorders (BD) in patients diagnosed with Major Depressive Disorder (MDD) or Unipolar Disorder (UD) in the clinical setting.<h4>Methods</h4>1,487 being treated for MDD or UD at 12 mental health centers across China, completed the MDQ and subsequently examined by the Mini International Neuropsychiatric Interview (MINI). Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II.<h4>Results</h4>Of the 1,487 patients, 309 (20.8%) satisfied the DSM-IV criteria for BD: 118 (7.9%) for BD-I and 191 (12.8%) for BD-II. When only part one of the MDQ was used, the best cutoff was 7 between BD and UD (sensitivity 0.66, specificity 0.88, positive predictive value 0.59, negative predictive value 0.91), 6 between BD-II and UD, and 10 between BD-I and BD-II. If all three parts of the MDQ were used, the MDQ could not distinguish between BD and UD at a cutoff of 7 (or 6), and the sensitivity was only 0.22 (or 0.24).<h4>Conclusion</h4>The Chinese version of the MDQ had good psychometric features in screening bipolar disorders from depressive patients with mood disorders when part two and part three of the MDQ were ignored.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0091895&type=printable |
| spellingShingle | Hai-Chen Yang Tie-Bang Liu Han Rong Jian-Qiang Bi Er-Ni Ji Hong-Jun Peng Xiao-Ping Wang Yi-Ru Fang Cheng-Mei Yuan Tian-Mei Si Zheng Lu Jian Hu Zhi-Yu Chen Yi Huang Jing Sun Hui-Chun Li Chen Hu Jin-Bei Zhang Ling-Jiang Li Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China. PLoS ONE |
| title | Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China. |
| title_full | Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China. |
| title_fullStr | Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China. |
| title_full_unstemmed | Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China. |
| title_short | Evaluation of Mood Disorder Questionnaire (MDQ) in patients with mood disorders: a multicenter trial across China. |
| title_sort | evaluation of mood disorder questionnaire mdq in patients with mood disorders a multicenter trial across china |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0091895&type=printable |
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