Chikungunya infection in infants
Abstract Introduction: the infection of chikungunya virus presents clinical manifestations variables, particularly in infants in which may present multiple cutaneous manifestations. Description: a case series study was carried out in an analytical character of 14 infants (>28 days to < 2 yea...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Instituto Materno Infantil de Pernambuco
|
| Series: | Revista Brasileira de Saúde Materno Infantil |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292016000800006&lng=en&tlng=en |
| _version_ | 1818494241684324352 |
|---|---|
| author | Maria do Carmo Menezes Bezerra Duarte Arino Faria de Oliveira Neto Patrícia Gomes de Matos Bezerra Lara Alves Cavalcanti Vanessa Máximo de Brito Silva Suelda Grasiela Alves Araújo de Abreu Susana Farias Batista Leite Nara Vasconcelos Cavalcanti |
| author_facet | Maria do Carmo Menezes Bezerra Duarte Arino Faria de Oliveira Neto Patrícia Gomes de Matos Bezerra Lara Alves Cavalcanti Vanessa Máximo de Brito Silva Suelda Grasiela Alves Araújo de Abreu Susana Farias Batista Leite Nara Vasconcelos Cavalcanti |
| author_sort | Maria do Carmo Menezes Bezerra Duarte |
| collection | DOAJ |
| description | Abstract Introduction: the infection of chikungunya virus presents clinical manifestations variables, particularly in infants in which may present multiple cutaneous manifestations. Description: a case series study was carried out in an analytical character of 14 infants (>28 days to < 2 years old) admitted in a hospital between November 2015 and January 2016 with suspected case of chikungunya, by a specific IgM reactive serology. Patients positive for dengue fever, Zika virus, bacterial infections and other exanthematic diseases were excluded. Fever and cutaneous alterations were the most frequent clinical manifestations in 100% of the cases, followed by irritability (64.3%), vomits and arthralgia/arthritis in 35.7% each. Three children presented alterations in the cerebrospinal fluid compatible to meningitis. Anemia frequency was 85.7%. The median white blood cells count was 7.700/mm3 (2.600 to 20.300/mm3). High levels of aminotransferases were observed in three cases (230 to 450 U/L). Antibiotic therapy was indicated in 64.3% of the cases. Two infants needed opioid derivatives for analgesia while others took acetaminophen and/or dipyrone. Discussion: the study shows evident multi-systemic involvement of chikungunya infection in infants. The treatment is supportive, giving special attention to hydration, analgesia, skin care, and rational use of antibiotic therapy. |
| first_indexed | 2024-12-10T18:03:59Z |
| format | Article |
| id | doaj.art-4d6d4b7f054d4a25bce9d35db763cd34 |
| institution | Directory Open Access Journal |
| issn | 1806-9304 |
| language | English |
| last_indexed | 2024-12-10T18:03:59Z |
| publisher | Instituto Materno Infantil de Pernambuco |
| record_format | Article |
| series | Revista Brasileira de Saúde Materno Infantil |
| spelling | doaj.art-4d6d4b7f054d4a25bce9d35db763cd342022-12-22T01:38:41ZengInstituto Materno Infantil de PernambucoRevista Brasileira de Saúde Materno Infantil1806-930416suppl 1S63S7110.1590/1806-9304201600s100006S1519-38292016000800006Chikungunya infection in infantsMaria do Carmo Menezes Bezerra DuarteArino Faria de Oliveira NetoPatrícia Gomes de Matos BezerraLara Alves CavalcantiVanessa Máximo de Brito SilvaSuelda Grasiela Alves Araújo de AbreuSusana Farias Batista LeiteNara Vasconcelos CavalcantiAbstract Introduction: the infection of chikungunya virus presents clinical manifestations variables, particularly in infants in which may present multiple cutaneous manifestations. Description: a case series study was carried out in an analytical character of 14 infants (>28 days to < 2 years old) admitted in a hospital between November 2015 and January 2016 with suspected case of chikungunya, by a specific IgM reactive serology. Patients positive for dengue fever, Zika virus, bacterial infections and other exanthematic diseases were excluded. Fever and cutaneous alterations were the most frequent clinical manifestations in 100% of the cases, followed by irritability (64.3%), vomits and arthralgia/arthritis in 35.7% each. Three children presented alterations in the cerebrospinal fluid compatible to meningitis. Anemia frequency was 85.7%. The median white blood cells count was 7.700/mm3 (2.600 to 20.300/mm3). High levels of aminotransferases were observed in three cases (230 to 450 U/L). Antibiotic therapy was indicated in 64.3% of the cases. Two infants needed opioid derivatives for analgesia while others took acetaminophen and/or dipyrone. Discussion: the study shows evident multi-systemic involvement of chikungunya infection in infants. The treatment is supportive, giving special attention to hydration, analgesia, skin care, and rational use of antibiotic therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292016000800006&lng=en&tlng=enChikungunyaCutaneous manifestationsInfants |
| spellingShingle | Maria do Carmo Menezes Bezerra Duarte Arino Faria de Oliveira Neto Patrícia Gomes de Matos Bezerra Lara Alves Cavalcanti Vanessa Máximo de Brito Silva Suelda Grasiela Alves Araújo de Abreu Susana Farias Batista Leite Nara Vasconcelos Cavalcanti Chikungunya infection in infants Revista Brasileira de Saúde Materno Infantil Chikungunya Cutaneous manifestations Infants |
| title | Chikungunya infection in infants |
| title_full | Chikungunya infection in infants |
| title_fullStr | Chikungunya infection in infants |
| title_full_unstemmed | Chikungunya infection in infants |
| title_short | Chikungunya infection in infants |
| title_sort | chikungunya infection in infants |
| topic | Chikungunya Cutaneous manifestations Infants |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292016000800006&lng=en&tlng=en |
| work_keys_str_mv | AT mariadocarmomenezesbezerraduarte chikungunyainfectionininfants AT arinofariadeoliveiraneto chikungunyainfectionininfants AT patriciagomesdematosbezerra chikungunyainfectionininfants AT laraalvescavalcanti chikungunyainfectionininfants AT vanessamaximodebritosilva chikungunyainfectionininfants AT sueldagrasielaalvesaraujodeabreu chikungunyainfectionininfants AT susanafariasbatistaleite chikungunyainfectionininfants AT naravasconceloscavalcanti chikungunyainfectionininfants |