Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography

This study evaluated the feasibility of deep-learning-based image reconstruction (DLIR) on coronary computed tomography angiography (CCTA). By using a 20 cm water phantom, the noise reduction ratio and noise power spectrum were evaluated according to the different reconstruction methods. Then 46 pat...

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Main Authors: Seul Ah Koo, Yunsub Jung, Kyoung A Um, Tae Hoon Kim, Ji Young Kim, Chul Hwan Park
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/10/3501
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author Seul Ah Koo
Yunsub Jung
Kyoung A Um
Tae Hoon Kim
Ji Young Kim
Chul Hwan Park
author_facet Seul Ah Koo
Yunsub Jung
Kyoung A Um
Tae Hoon Kim
Ji Young Kim
Chul Hwan Park
author_sort Seul Ah Koo
collection DOAJ
description This study evaluated the feasibility of deep-learning-based image reconstruction (DLIR) on coronary computed tomography angiography (CCTA). By using a 20 cm water phantom, the noise reduction ratio and noise power spectrum were evaluated according to the different reconstruction methods. Then 46 patients who underwent CCTA were retrospectively enrolled. CCTA was performed using the 16 cm coverage axial volume scan technique. All CT images were reconstructed using filtered back projection (FBP); three model-based iterative reconstructions (MBIR) of 40%, 60%, and 80%; and three DLIR algorithms: low (L), medium (M), and high (H). Quantitative and qualitative image qualities of CCTA were compared according to the reconstruction methods. In the phantom study, the noise reduction ratios of MBIR-40%, MBIR-60%, MBIR-80%, DLIR-L, DLIR-M, and DLIR-H were 26.7 ± 0.2%, 39.5 ± 0.5%, 51.7 ± 0.4%, 33.1 ± 0.8%, 43.2 ± 0.8%, and 53.5 ± 0.1%, respectively. The pattern of the noise power spectrum of the DLIR images was more similar to FBP images than MBIR images. In a CCTA study, CCTA yielded a significantly lower noise index with DLIR-H reconstruction than with the other reconstruction methods. DLIR-H showed a higher SNR and CNR than MBIR (<i>p</i> < 0.05). The qualitative image quality of CCTA with DLIR-H was significantly higher than that of MBIR-80% or FBP. The DLIR algorithm was feasible and yielded a better image quality than the FBP or MBIR algorithms on CCTA.
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spelling doaj.art-4d6ed664f2b54506afef1a6a3f058bd92023-11-18T01:54:05ZengMDPI AGJournal of Clinical Medicine2077-03832023-05-011210350110.3390/jcm12103501Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography AngiographySeul Ah Koo0Yunsub Jung1Kyoung A Um2Tae Hoon Kim3Ji Young Kim4Chul Hwan Park5Department of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaResearch Team, GE Healthcare Korea, Seoul 04637, Republic of KoreaResearch Team, GE Healthcare Korea, Seoul 04637, Republic of KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaDepartment of Radiology and The Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of KoreaThis study evaluated the feasibility of deep-learning-based image reconstruction (DLIR) on coronary computed tomography angiography (CCTA). By using a 20 cm water phantom, the noise reduction ratio and noise power spectrum were evaluated according to the different reconstruction methods. Then 46 patients who underwent CCTA were retrospectively enrolled. CCTA was performed using the 16 cm coverage axial volume scan technique. All CT images were reconstructed using filtered back projection (FBP); three model-based iterative reconstructions (MBIR) of 40%, 60%, and 80%; and three DLIR algorithms: low (L), medium (M), and high (H). Quantitative and qualitative image qualities of CCTA were compared according to the reconstruction methods. In the phantom study, the noise reduction ratios of MBIR-40%, MBIR-60%, MBIR-80%, DLIR-L, DLIR-M, and DLIR-H were 26.7 ± 0.2%, 39.5 ± 0.5%, 51.7 ± 0.4%, 33.1 ± 0.8%, 43.2 ± 0.8%, and 53.5 ± 0.1%, respectively. The pattern of the noise power spectrum of the DLIR images was more similar to FBP images than MBIR images. In a CCTA study, CCTA yielded a significantly lower noise index with DLIR-H reconstruction than with the other reconstruction methods. DLIR-H showed a higher SNR and CNR than MBIR (<i>p</i> < 0.05). The qualitative image quality of CCTA with DLIR-H was significantly higher than that of MBIR-80% or FBP. The DLIR algorithm was feasible and yielded a better image quality than the FBP or MBIR algorithms on CCTA.https://www.mdpi.com/2077-0383/12/10/3501coronary computed tomographic angiographydeep learning-based image reconstructionimage quality
spellingShingle Seul Ah Koo
Yunsub Jung
Kyoung A Um
Tae Hoon Kim
Ji Young Kim
Chul Hwan Park
Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography
Journal of Clinical Medicine
coronary computed tomographic angiography
deep learning-based image reconstruction
image quality
title Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography
title_full Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography
title_fullStr Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography
title_full_unstemmed Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography
title_short Clinical Feasibility of Deep Learning-Based Image Reconstruction on Coronary Computed Tomography Angiography
title_sort clinical feasibility of deep learning based image reconstruction on coronary computed tomography angiography
topic coronary computed tomographic angiography
deep learning-based image reconstruction
image quality
url https://www.mdpi.com/2077-0383/12/10/3501
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