Identifying small molecules for protecting chondrocyte function and matrix integrity after controlled compressive injury

Identifying small molecules for protecting chondrocyte function and matrix integrity after controlled compressive injury

Objective: Articular cartilage injury is central for the development of post-traumatic osteoarthritis (PTOA). With few disease-modifying therapies successful at offsetting progressive osteoarthritis (OA), our goal is to use a high throughput screening platform of cartilage injury to identify novel c...

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Bibliographic Details
Main Authors: Saleh Al Jundi, Jerahme R. Martinez, Jake Cresta, Farzad Yousefi, Gabriel DeSantis, Matthew Thoonkuzhy, Emilie Rabut, Bhavana Mohanraj, Robert L. Mauck, George R. Dodge
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Joint
Trauma
Osteoarthritis
High-throughput
Screen
Drug
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913122000577

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