Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity

Trichilemmal carcinoma (TC) is a rare malignant adnexal neoplasm, falling under the umbrella of tumors with follicular differentiation generally presenting as papulonodular growth with surface ulceration over sun-exposed skin. Histologically, it mimics tumors such as basal cell carcinoma, sebaceous...

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Main Authors: Archana Shetty, Aparna Muralidhar, Nidha Gaffoor
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Archives of Medicine and Health Sciences
Subjects:
Online Access:http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2021;volume=9;issue=2;spage=317;epage=319;aulast=Shetty
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author Archana Shetty
Aparna Muralidhar
Nidha Gaffoor
author_facet Archana Shetty
Aparna Muralidhar
Nidha Gaffoor
author_sort Archana Shetty
collection DOAJ
description Trichilemmal carcinoma (TC) is a rare malignant adnexal neoplasm, falling under the umbrella of tumors with follicular differentiation generally presenting as papulonodular growth with surface ulceration over sun-exposed skin. Histologically, it mimics tumors such as basal cell carcinoma, sebaceous carcinoma, squamous cell carcinoma, and malignant proliferating trichilemmal tumors. As there is a difference of opinion regarding the histopathological criteria for TC, a definitive diagnosis should be confined to cases having the majority of histomorphological findings with immunohistochemical corroboration to help define the clinicopathological behavior of this disease. Rarity, indolent clinical course in spite of local aggressiveness and a good survival rate postexcision further undermine the importance of this unique entity.
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spelling doaj.art-4d71436cd884461f80532da5f2c58c2d2022-12-21T19:35:10ZengWolters Kluwer Medknow PublicationsArchives of Medicine and Health Sciences2321-48482021-01-019231731910.4103/amhs.amhs_99_21Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entityArchana ShettyAparna MuralidharNidha GaffoorTrichilemmal carcinoma (TC) is a rare malignant adnexal neoplasm, falling under the umbrella of tumors with follicular differentiation generally presenting as papulonodular growth with surface ulceration over sun-exposed skin. Histologically, it mimics tumors such as basal cell carcinoma, sebaceous carcinoma, squamous cell carcinoma, and malignant proliferating trichilemmal tumors. As there is a difference of opinion regarding the histopathological criteria for TC, a definitive diagnosis should be confined to cases having the majority of histomorphological findings with immunohistochemical corroboration to help define the clinicopathological behavior of this disease. Rarity, indolent clinical course in spite of local aggressiveness and a good survival rate postexcision further undermine the importance of this unique entity.http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2021;volume=9;issue=2;spage=317;epage=319;aulast=Shettyhair follicleimmunohistochemistryskin appendageworld health organization
spellingShingle Archana Shetty
Aparna Muralidhar
Nidha Gaffoor
Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity
Archives of Medicine and Health Sciences
hair follicle
immunohistochemistry
skin appendage
world health organization
title Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity
title_full Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity
title_fullStr Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity
title_full_unstemmed Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity
title_short Trichilemmal carcinoma of the scalp: Demystifying anecdote of a rare entity
title_sort trichilemmal carcinoma of the scalp demystifying anecdote of a rare entity
topic hair follicle
immunohistochemistry
skin appendage
world health organization
url http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2021;volume=9;issue=2;spage=317;epage=319;aulast=Shetty
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AT aparnamuralidhar trichilemmalcarcinomaofthescalpdemystifyinganecdoteofarareentity
AT nidhagaffoor trichilemmalcarcinomaofthescalpdemystifyinganecdoteofarareentity