Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties
Saussureae Involucratae Herba is the dried ground part of Saussurea involucrata (Kar. et Kir.) Sch.-Bip, which is also named as “Snow lotus” and being used in traditional Uyghur and/or Chinese medicine. This rare herb can be found at 4,000 m elevation in western part of Tianshan Mountain, Xinjiang C...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-01-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2019.01549/full |
| _version_ | 1818517635522887680 |
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| author | Guowei Gong Jing Huang Yang Yang Baohui Qi Guangyi Han Yuzhong Zheng Huan He Kelvin Chan Karl WK Tsim Karl WK Tsim Tina TX Dong Tina TX Dong |
| author_facet | Guowei Gong Jing Huang Yang Yang Baohui Qi Guangyi Han Yuzhong Zheng Huan He Kelvin Chan Karl WK Tsim Karl WK Tsim Tina TX Dong Tina TX Dong |
| author_sort | Guowei Gong |
| collection | DOAJ |
| description | Saussureae Involucratae Herba is the dried ground part of Saussurea involucrata (Kar. et Kir.) Sch.-Bip, which is also named as “Snow lotus” and being used in traditional Uyghur and/or Chinese medicine. This rare herb can be found at 4,000 m elevation in western part of Tianshan Mountain, Xinjiang China. According to China Pharmacopoeia (2015), the major pharmaceutical values of “Snow lotus” (Xuě liánhuā in Chinese) are alleviating rheumatoid arthritis, accelerating blood circulation and mitigating other “cold” syndromes. Traditionally, the clinical application of “Snow lotus” includes the treatments in inflammation-associated disorder, blood circulation acceleration and heat and dampness elimination. Recent studies suggested that “Snow lotus” possessed therapeutic effects associating with anti-cancer, anti-oxidation, adipogenesis suppression and neuroprotection activities, which were proposed to be related with its bioactive constitutes, i.e. acacetin, hispidulin, and rutin. In the present review, we aim to summarize pharmacological effects and underlying cell signaling pathways of “Snow lotus” in treating various medical problems. |
| first_indexed | 2024-12-11T00:58:55Z |
| format | Article |
| id | doaj.art-4d7297bd560744cbafecad7374796466 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-11T00:58:55Z |
| publishDate | 2020-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-4d7297bd560744cbafecad73747964662022-12-22T01:26:23ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-01-011010.3389/fphar.2019.01549464900Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological PropertiesGuowei Gong0Jing Huang1Yang Yang2Baohui Qi3Guangyi Han4Yuzhong Zheng5Huan He6Kelvin Chan7Karl WK Tsim8Karl WK Tsim9Tina TX Dong10Tina TX Dong11Department of Biological Engineering, Zunyi Medical University, Zhuhai, ChinaCollege of Environmental and Biological Engineering, Putian University, Putian, ChinaDepartment of Biological Engineering, Zunyi Medical University, Zhuhai, ChinaDepartment of Biological Engineering, Zunyi Medical University, Zhuhai, ChinaGansu Institute for Drug Control, Lanzhou, ChinaDepartment of Biology, Hanshan Normal University, Chaozhou, ChinaDepartment of Biological Engineering, Zunyi Medical University, Zhuhai, ChinaSchool of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Liverpool, United KingdomShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, ChinaDivision of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, Hong KongShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, ChinaDivision of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, Hong KongSaussureae Involucratae Herba is the dried ground part of Saussurea involucrata (Kar. et Kir.) Sch.-Bip, which is also named as “Snow lotus” and being used in traditional Uyghur and/or Chinese medicine. This rare herb can be found at 4,000 m elevation in western part of Tianshan Mountain, Xinjiang China. According to China Pharmacopoeia (2015), the major pharmaceutical values of “Snow lotus” (Xuě liánhuā in Chinese) are alleviating rheumatoid arthritis, accelerating blood circulation and mitigating other “cold” syndromes. Traditionally, the clinical application of “Snow lotus” includes the treatments in inflammation-associated disorder, blood circulation acceleration and heat and dampness elimination. Recent studies suggested that “Snow lotus” possessed therapeutic effects associating with anti-cancer, anti-oxidation, adipogenesis suppression and neuroprotection activities, which were proposed to be related with its bioactive constitutes, i.e. acacetin, hispidulin, and rutin. In the present review, we aim to summarize pharmacological effects and underlying cell signaling pathways of “Snow lotus” in treating various medical problems.https://www.frontiersin.org/article/10.3389/fphar.2019.01549/fullSaussureae Involucratae Herbatraditional Chinese medicinetraditional Uyghur medicineherbal medicineSnow lotus |
| spellingShingle | Guowei Gong Jing Huang Yang Yang Baohui Qi Guangyi Han Yuzhong Zheng Huan He Kelvin Chan Karl WK Tsim Karl WK Tsim Tina TX Dong Tina TX Dong Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties Frontiers in Pharmacology Saussureae Involucratae Herba traditional Chinese medicine traditional Uyghur medicine herbal medicine Snow lotus |
| title | Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties |
| title_full | Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties |
| title_fullStr | Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties |
| title_full_unstemmed | Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties |
| title_short | Saussureae Involucratae Herba (Snow Lotus): Review of Chemical Compositions and Pharmacological Properties |
| title_sort | saussureae involucratae herba snow lotus review of chemical compositions and pharmacological properties |
| topic | Saussureae Involucratae Herba traditional Chinese medicine traditional Uyghur medicine herbal medicine Snow lotus |
| url | https://www.frontiersin.org/article/10.3389/fphar.2019.01549/full |
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