Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections

In this retrospective cohort study, we evaluated the predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swabs for the development of MRSA infections in patients with left ventricular assist devices. In 106 patients, the MRSA nasal swab had a negative predictive value of 92....

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Main Authors: Lauren J. Koscal, Holly Meadows, Brian R. Raux, Krutika N. Mediwala, Erin Weeda, Brian Houston, Deeksha Jandhyala, Jaclyn M. Hawn
Format: Article
Language:English
Published: Cambridge University Press 2022-01-01
Series:Antimicrobial Stewardship & Healthcare Epidemiology
Online Access:https://www.cambridge.org/core/product/identifier/S2732494X22000468/type/journal_article
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author Lauren J. Koscal
Holly Meadows
Brian R. Raux
Krutika N. Mediwala
Erin Weeda
Brian Houston
Deeksha Jandhyala
Jaclyn M. Hawn
author_facet Lauren J. Koscal
Holly Meadows
Brian R. Raux
Krutika N. Mediwala
Erin Weeda
Brian Houston
Deeksha Jandhyala
Jaclyn M. Hawn
author_sort Lauren J. Koscal
collection DOAJ
description In this retrospective cohort study, we evaluated the predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swabs for the development of MRSA infections in patients with left ventricular assist devices. In 106 patients, the MRSA nasal swab had a negative predictive value of 92.9% demonstrating a potential role in antibiotic de-escalation.
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spelling doaj.art-4d7a0f01c6d04b399278ef2dfbc00c092023-03-09T12:28:16ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2022-01-01210.1017/ash.2022.46Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infectionsLauren J. Koscal0https://orcid.org/0000-0002-6686-3541Holly Meadows1Brian R. Raux2Krutika N. Mediwala3https://orcid.org/0000-0002-3982-2103Erin Weeda4https://orcid.org/0000-0001-7876-5802Brian Houston5https://orcid.org/0000-0001-6188-8072Deeksha Jandhyala6Jaclyn M. Hawn7https://orcid.org/0000-0002-5992-7375Department of Pharmacy, University of Florida Health at Jacksonville, Jacksonville, FloridaDepartment of Pharmacy, Medical University of South Carolina, Charleston, South CarolinaDepartment of Pharmacy, Medical University of South Carolina, Charleston, South CarolinaDepartment of Pharmacy, Medical University of South Carolina, Charleston, South CarolinaMedical University of South Carolina, College of Pharmacy, Charleston, South CarolinaDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South CarolinaDivision of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, South CarolinaDepartment of Pharmacy, Medical University of South Carolina, Charleston, South CarolinaIn this retrospective cohort study, we evaluated the predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swabs for the development of MRSA infections in patients with left ventricular assist devices. In 106 patients, the MRSA nasal swab had a negative predictive value of 92.9% demonstrating a potential role in antibiotic de-escalation.https://www.cambridge.org/core/product/identifier/S2732494X22000468/type/journal_article
spellingShingle Lauren J. Koscal
Holly Meadows
Brian R. Raux
Krutika N. Mediwala
Erin Weeda
Brian Houston
Deeksha Jandhyala
Jaclyn M. Hawn
Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections
Antimicrobial Stewardship & Healthcare Epidemiology
title Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections
title_full Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections
title_fullStr Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections
title_full_unstemmed Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections
title_short Evaluation of the impact of nasal colonization with methicillin-resistant Staphylococcus aureus on left ventricular assist device infections
title_sort evaluation of the impact of nasal colonization with methicillin resistant staphylococcus aureus on left ventricular assist device infections
url https://www.cambridge.org/core/product/identifier/S2732494X22000468/type/journal_article
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