Quercetin, a Flavonoid with Great Pharmacological Capacity
Quercetin is a flavonoid with a low molecular weight that belongs to the human diet’s phenolic phytochemicals and nonenergy constituents. Quercetin has a potent antioxidant capacity, being able to capture reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive chlorine species (...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/29/5/1000 |
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| author | Eber Josue Carrillo-Martinez Flor Yohana Flores-Hernández Adriana María Salazar-Montes Hector Fabián Nario-Chaidez Luis Daniel Hernández-Ortega |
| author_facet | Eber Josue Carrillo-Martinez Flor Yohana Flores-Hernández Adriana María Salazar-Montes Hector Fabián Nario-Chaidez Luis Daniel Hernández-Ortega |
| author_sort | Eber Josue Carrillo-Martinez |
| collection | DOAJ |
| description | Quercetin is a flavonoid with a low molecular weight that belongs to the human diet’s phenolic phytochemicals and nonenergy constituents. Quercetin has a potent antioxidant capacity, being able to capture reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive chlorine species (ROC), which act as reducing agents by chelating transition-metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, different pharmacological properties of quercetin have been described, such as carcinostatic properties; antiviral, antihypertensive, and anti-inflammatory properties; the ability to protect low-density lipoprotein (LDL) oxidation, and the ability to inhibit angiogenesis; these are developed in this review. |
| first_indexed | 2024-04-25T00:24:15Z |
| format | Article |
| id | doaj.art-4d8020c200564e29a358e48c1f09b039 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-25T00:24:15Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-4d8020c200564e29a358e48c1f09b0392024-03-12T16:50:42ZengMDPI AGMolecules1420-30492024-02-01295100010.3390/molecules29051000Quercetin, a Flavonoid with Great Pharmacological CapacityEber Josue Carrillo-Martinez0Flor Yohana Flores-Hernández1Adriana María Salazar-Montes2Hector Fabián Nario-Chaidez3Luis Daniel Hernández-Ortega4Unidad de Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara 44270, MexicoUnidad de Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara 44270, MexicoInstituto de Investigación en Enfermedades Crónico-Degenerativas, Centro de Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Guadalajara 44340, MexicoSistemas y Servicios Oncológicos de Latinoamérica S.A. de C.V., Zapopan 45079, MexicoCentro de Investigación Multidisciplinaria en Salud, Centro Universitario de Tonalá, Universidad de Guadalajara, Tonalá 45425, MexicoQuercetin is a flavonoid with a low molecular weight that belongs to the human diet’s phenolic phytochemicals and nonenergy constituents. Quercetin has a potent antioxidant capacity, being able to capture reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive chlorine species (ROC), which act as reducing agents by chelating transition-metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, different pharmacological properties of quercetin have been described, such as carcinostatic properties; antiviral, antihypertensive, and anti-inflammatory properties; the ability to protect low-density lipoprotein (LDL) oxidation, and the ability to inhibit angiogenesis; these are developed in this review.https://www.mdpi.com/1420-3049/29/5/1000quercetinantioxidantfree radicalspharmacological propertiesnanoparticles |
| spellingShingle | Eber Josue Carrillo-Martinez Flor Yohana Flores-Hernández Adriana María Salazar-Montes Hector Fabián Nario-Chaidez Luis Daniel Hernández-Ortega Quercetin, a Flavonoid with Great Pharmacological Capacity Molecules quercetin antioxidant free radicals pharmacological properties nanoparticles |
| title | Quercetin, a Flavonoid with Great Pharmacological Capacity |
| title_full | Quercetin, a Flavonoid with Great Pharmacological Capacity |
| title_fullStr | Quercetin, a Flavonoid with Great Pharmacological Capacity |
| title_full_unstemmed | Quercetin, a Flavonoid with Great Pharmacological Capacity |
| title_short | Quercetin, a Flavonoid with Great Pharmacological Capacity |
| title_sort | quercetin a flavonoid with great pharmacological capacity |
| topic | quercetin antioxidant free radicals pharmacological properties nanoparticles |
| url | https://www.mdpi.com/1420-3049/29/5/1000 |
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