Fluoride and Pineal Gland
The pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle. Due to its exceptionally high vascularization and its location outside the blood–brain barrier, the pineal gl...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/8/2885 |
| _version_ | 1797569926677921792 |
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| author | Dariusz Chlubek Maciej Sikora |
| author_facet | Dariusz Chlubek Maciej Sikora |
| author_sort | Dariusz Chlubek |
| collection | DOAJ |
| description | The pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle. Due to its exceptionally high vascularization and its location outside the blood–brain barrier, the pineal gland may accumulate significant amounts of calcium and fluoride, making it the most fluoride-saturated organ of the human body. Both the calcification and accumulation of fluoride may result in melatonin deficiency. |
| first_indexed | 2024-03-10T20:18:14Z |
| format | Article |
| id | doaj.art-4d8360e68e384672bb265181b6e709d8 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T20:18:14Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-4d8360e68e384672bb265181b6e709d82023-11-19T22:23:30ZengMDPI AGApplied Sciences2076-34172020-04-01108288510.3390/app10082885Fluoride and Pineal GlandDariusz Chlubek0Maciej Sikora1Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Powstańców Wlkp. 72, 70-111 Szczecin, PolandDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University, Powstańców Wlkp. 72, 70-111 Szczecin, PolandThe pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle. Due to its exceptionally high vascularization and its location outside the blood–brain barrier, the pineal gland may accumulate significant amounts of calcium and fluoride, making it the most fluoride-saturated organ of the human body. Both the calcification and accumulation of fluoride may result in melatonin deficiency.https://www.mdpi.com/2076-3417/10/8/2885fluoridepineal glandcalcification of soft tissuesmelatonin |
| spellingShingle | Dariusz Chlubek Maciej Sikora Fluoride and Pineal Gland Applied Sciences fluoride pineal gland calcification of soft tissues melatonin |
| title | Fluoride and Pineal Gland |
| title_full | Fluoride and Pineal Gland |
| title_fullStr | Fluoride and Pineal Gland |
| title_full_unstemmed | Fluoride and Pineal Gland |
| title_short | Fluoride and Pineal Gland |
| title_sort | fluoride and pineal gland |
| topic | fluoride pineal gland calcification of soft tissues melatonin |
| url | https://www.mdpi.com/2076-3417/10/8/2885 |
| work_keys_str_mv | AT dariuszchlubek fluorideandpinealgland AT maciejsikora fluorideandpinealgland |