Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity
Acute disseminated encephalomyelitis (ADEM), also called post-infectious encephalomyelitis, is defined as an immune-mediated inflammatory and demyelinating event that involves the central nervous system. It usually follows an infectious episode or an active immunization several weeks prior the disea...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043321005860 |
| _version_ | 1818662963920240640 |
|---|---|
| author | Rachid Belfkih, Professor of neurology Omar Ghomari Khayat, MD |
| author_facet | Rachid Belfkih, Professor of neurology Omar Ghomari Khayat, MD |
| author_sort | Rachid Belfkih, Professor of neurology |
| collection | DOAJ |
| description | Acute disseminated encephalomyelitis (ADEM), also called post-infectious encephalomyelitis, is defined as an immune-mediated inflammatory and demyelinating event that involves the central nervous system. It usually follows an infectious episode or an active immunization several weeks prior the disease onset. ADEM is typically presented with an encephalopathy associated to focal neurological signs. Cerebrospinal fluid analysis is usually nonspecific, showing signs of central nervous system inflammation with negative viral and bacterial cultures. The diagnosis is based on clinical and MRI findings. Patients with ADEM respond well to anti-inflammatory and immunosuppressive agents, with high-dose of intravenous steroids administered as first-line treatment. Herein, we present the case of a 7-year-old male patient diagnosed of acute disseminated encephalomyelitis most likely secondary to a viral upper respiratory tract infection. It is a unique case, as the inaugurating sign is an acute onset anarthria. The patient responded favorably to the first-line therapy with an almost full recovery within the first week of treatment. |
| first_indexed | 2024-12-17T05:09:18Z |
| format | Article |
| id | doaj.art-4d87fdfbb9a0410e891fbdb942ce9d4f |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-17T05:09:18Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-4d87fdfbb9a0410e891fbdb942ce9d4f2022-12-21T22:02:18ZengElsevierRadiology Case Reports1930-04332021-11-01161134183421Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entityRachid Belfkih, Professor of neurology0Omar Ghomari Khayat, MD1Abdelmalek Saadi University, Faculty of medicine and pharmacy of Tangier, Tangier, Morocco; Department of neurology, University Hospital Center of Tangier-Tetouan-Al hoceima, Tangier, Morocco; Corresponding author.Abdelmalek Saadi University, Faculty of medicine and pharmacy of Tangier, Tangier, Morocco; Department of neurology, University Hospital Center of Tangier-Tetouan-Al hoceima, Tangier, MoroccoAcute disseminated encephalomyelitis (ADEM), also called post-infectious encephalomyelitis, is defined as an immune-mediated inflammatory and demyelinating event that involves the central nervous system. It usually follows an infectious episode or an active immunization several weeks prior the disease onset. ADEM is typically presented with an encephalopathy associated to focal neurological signs. Cerebrospinal fluid analysis is usually nonspecific, showing signs of central nervous system inflammation with negative viral and bacterial cultures. The diagnosis is based on clinical and MRI findings. Patients with ADEM respond well to anti-inflammatory and immunosuppressive agents, with high-dose of intravenous steroids administered as first-line treatment. Herein, we present the case of a 7-year-old male patient diagnosed of acute disseminated encephalomyelitis most likely secondary to a viral upper respiratory tract infection. It is a unique case, as the inaugurating sign is an acute onset anarthria. The patient responded favorably to the first-line therapy with an almost full recovery within the first week of treatment.http://www.sciencedirect.com/science/article/pii/S1930043321005860Case reportAcute disseminated encephalomyelitisMultiple sclerosisAnti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodiesCorticosteroids |
| spellingShingle | Rachid Belfkih, Professor of neurology Omar Ghomari Khayat, MD Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity Radiology Case Reports Case report Acute disseminated encephalomyelitis Multiple sclerosis Anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies Corticosteroids |
| title | Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity |
| title_full | Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity |
| title_fullStr | Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity |
| title_full_unstemmed | Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity |
| title_short | Acute onset anarthria in a 7-year-old patient as a presentation of acute disseminated encephalomyelitis: A rare clinical and radiological entity |
| title_sort | acute onset anarthria in a 7 year old patient as a presentation of acute disseminated encephalomyelitis a rare clinical and radiological entity |
| topic | Case report Acute disseminated encephalomyelitis Multiple sclerosis Anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies Corticosteroids |
| url | http://www.sciencedirect.com/science/article/pii/S1930043321005860 |
| work_keys_str_mv | AT rachidbelfkihprofessorofneurology acuteonsetanarthriaina7yearoldpatientasapresentationofacutedisseminatedencephalomyelitisarareclinicalandradiologicalentity AT omarghomarikhayatmd acuteonsetanarthriaina7yearoldpatientasapresentationofacutedisseminatedencephalomyelitisarareclinicalandradiologicalentity |