Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories

The study was conducted on seventy individuals of both genders who have been exposed to human cytomegalovirus, a common illness in Iraq. Total cases of human cytomegvirus associated with malignant brain tumors were detected by a real time PCR technique. This resulted in only thirty-six cases of true...

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Bibliographic Details
Main Authors: Alameedy Fadyia Mahdi Muslim, Al-mashhadi Abbas Raheem Jebur
Format: Article
Language:English
Published: Sciendo 2020-03-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:http://www.degruyter.com/view/j/cipms.2020.33.issue-1/cipms-2020-0004/cipms-2020-0004.xml?format=INT
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Summary:The study was conducted on seventy individuals of both genders who have been exposed to human cytomegalovirus, a common illness in Iraq. Total cases of human cytomegvirus associated with malignant brain tumors were detected by a real time PCR technique. This resulted in only thirty-six cases of true infection. Of these 24 cases were female, while 12 cases of male infected. The titer to assay the presence of anti- and pro-inflammatories was assessed in sera of all patients by using ELISA kits to evaluate cytokines. This indicated that the pro-inflammatory IL12, after seven days increased (1.67±0.23 pg/ml), while IL4, an anti-inflammatory, decreased to reach (0.39±0.16 pg/ml) (at p<0.05) in the plasm of the experimental patients compared with the control group.
ISSN:2300-6676