Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories
The study was conducted on seventy individuals of both genders who have been exposed to human cytomegalovirus, a common illness in Iraq. Total cases of human cytomegvirus associated with malignant brain tumors were detected by a real time PCR technique. This resulted in only thirty-six cases of true...
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| Format: | Article |
| Language: | English |
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Sciendo
2020-03-01
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| Series: | Current Issues in Pharmacy and Medical Sciences |
| Subjects: | |
| Online Access: | http://www.degruyter.com/view/j/cipms.2020.33.issue-1/cipms-2020-0004/cipms-2020-0004.xml?format=INT |
| _version_ | 1811331580203892736 |
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| author | Alameedy Fadyia Mahdi Muslim Al-mashhadi Abbas Raheem Jebur |
| author_facet | Alameedy Fadyia Mahdi Muslim Al-mashhadi Abbas Raheem Jebur |
| author_sort | Alameedy Fadyia Mahdi Muslim |
| collection | DOAJ |
| description | The study was conducted on seventy individuals of both genders who have been exposed to human cytomegalovirus, a common illness in Iraq. Total cases of human cytomegvirus associated with malignant brain tumors were detected by a real time PCR technique. This resulted in only thirty-six cases of true infection. Of these 24 cases were female, while 12 cases of male infected. The titer to assay the presence of anti- and pro-inflammatories was assessed in sera of all patients by using ELISA kits to evaluate cytokines. This indicated that the pro-inflammatory IL12, after seven days increased (1.67±0.23 pg/ml), while IL4, an anti-inflammatory, decreased to reach (0.39±0.16 pg/ml) (at p<0.05) in the plasm of the experimental patients compared with the control group. |
| first_indexed | 2024-04-13T16:22:51Z |
| format | Article |
| id | doaj.art-4d88c9458fe84689a8de1a33f8b81864 |
| institution | Directory Open Access Journal |
| issn | 2300-6676 |
| language | English |
| last_indexed | 2024-04-13T16:22:51Z |
| publishDate | 2020-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Current Issues in Pharmacy and Medical Sciences |
| spelling | doaj.art-4d88c9458fe84689a8de1a33f8b818642022-12-22T02:39:49ZengSciendoCurrent Issues in Pharmacy and Medical Sciences2300-66762020-03-01331141610.2478/cipms-2020-0004cipms-2020-0004Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatoriesAlameedy Fadyia Mahdi Muslim0Al-mashhadi Abbas Raheem Jebur1Faculty of Science, Kufa University, Najaf, IraqFaculity of Medicine, Kufa University, Najaf, IraqThe study was conducted on seventy individuals of both genders who have been exposed to human cytomegalovirus, a common illness in Iraq. Total cases of human cytomegvirus associated with malignant brain tumors were detected by a real time PCR technique. This resulted in only thirty-six cases of true infection. Of these 24 cases were female, while 12 cases of male infected. The titer to assay the presence of anti- and pro-inflammatories was assessed in sera of all patients by using ELISA kits to evaluate cytokines. This indicated that the pro-inflammatory IL12, after seven days increased (1.67±0.23 pg/ml), while IL4, an anti-inflammatory, decreased to reach (0.39±0.16 pg/ml) (at p<0.05) in the plasm of the experimental patients compared with the control group.http://www.degruyter.com/view/j/cipms.2020.33.issue-1/cipms-2020-0004/cipms-2020-0004.xml?format=INTcmvicamspssrt-pcr |
| spellingShingle | Alameedy Fadyia Mahdi Muslim Al-mashhadi Abbas Raheem Jebur Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories Current Issues in Pharmacy and Medical Sciences cmv icam spss rt-pcr |
| title | Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories |
| title_full | Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories |
| title_fullStr | Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories |
| title_full_unstemmed | Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories |
| title_short | Diagnosis of human cytomegvirus association with malignant gliomas and pro- and anti-inflammatories |
| title_sort | diagnosis of human cytomegvirus association with malignant gliomas and pro and anti inflammatories |
| topic | cmv icam spss rt-pcr |
| url | http://www.degruyter.com/view/j/cipms.2020.33.issue-1/cipms-2020-0004/cipms-2020-0004.xml?format=INT |
| work_keys_str_mv | AT alameedyfadyiamahdimuslim diagnosisofhumancytomegvirusassociationwithmalignantgliomasandproandantiinflammatories AT almashhadiabbasraheemjebur diagnosisofhumancytomegvirusassociationwithmalignantgliomasandproandantiinflammatories |