A Repeated Time-to-Positive Symptoms Improvement among Malaysian Patients with Schizophrenia Spectrum Disorders Treated with Clozapine

A Repeated Time-to-Positive Symptoms Improvement among Malaysian Patients with Schizophrenia Spectrum Disorders Treated with Clozapine

Clozapine remains the drug of choice for resistant schizophrenia. However, its dose-response relationship is still controversial. The current investigation aimed to develop a repeated time-to-positive symptoms improvement following the onset of clozapine treatment in Malaysian schizophrenia spectrum...

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Bibliographic Details
Main Authors: Orwa Albitar, Sabariah Noor Harun, Siti Nor Aizah Ahmad, Siti Maisharah Sheikh Ghadzi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
clozapine
repeated time-to-event
hazard
NONMEM
positive symptoms
Online Access:https://www.mdpi.com/1999-4923/13/8/1121

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