Oral Fucoidan Attenuates Lung Pathology and Clinical Signs in a Severe Influenza A Mouse Model

Oral Fucoidan Attenuates Lung Pathology and Clinical Signs in a Severe Influenza A Mouse Model

Fucoidans are known to be effective inhibitors of inflammation, and of virus binding and cellular entry. <i>Undaria pinnatifida</i>-derived fucoidan (UPF) was assessed in a severe influenza A (H1N1, PR8) infection model in mice. Initially, UPF was gavaged at 3.52 mg daily in a treatment...

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Bibliographic Details
Main Authors: Claire Richards, Neil A. Williams, J. Helen Fitton, Damien N. Stringer, Samuel S. Karpiniec, Ah Young Park
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Marine Drugs
Subjects:
anti-viral
fucoidan
influenza
inflammation
mice
lung
Online Access:https://www.mdpi.com/1660-3397/18/5/246

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