A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research
Therapeutic DNAzymes with RNA depleting effect are multifunctional building blocks for constructing biological materials. In a recent work published in Nature Chemistry, Holliger group and Chaput group had a wonderful debate base on previously reported approach for tailoring DNAzymes with high mRNA...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2023-12-01
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| Series: | Biomedical Technology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949723X23000041 |
| _version_ | 1797630965797879808 |
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| author | Jiaqi Yan Meixin Ran Hongbo Zhang |
| author_facet | Jiaqi Yan Meixin Ran Hongbo Zhang |
| author_sort | Jiaqi Yan |
| collection | DOAJ |
| description | Therapeutic DNAzymes with RNA depleting effect are multifunctional building blocks for constructing biological materials. In a recent work published in Nature Chemistry, Holliger group and Chaput group had a wonderful debate base on previously reported approach for tailoring DNAzymes with high mRNA cleavage activity in mammalian cells. Their perspective pushes the catalytic mechanism investigation of DNAzymes to a new stage with more standardization and clarity. |
| first_indexed | 2024-03-11T11:15:23Z |
| format | Article |
| id | doaj.art-4d90cbbae06b4805b50fabd522729282 |
| institution | Directory Open Access Journal |
| issn | 2949-723X |
| language | English |
| last_indexed | 2024-03-11T11:15:23Z |
| publishDate | 2023-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Biomedical Technology |
| spelling | doaj.art-4d90cbbae06b4805b50fabd5227292822023-11-11T04:28:51ZengKeAi Communications Co., Ltd.Biomedical Technology2949-723X2023-12-0142123A scientific debate: The sword that cleaves chaos of DNAzyme catalysis researchJiaqi Yan0Meixin Ran1Hongbo Zhang2Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, FinlandPharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, FinlandPharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland; Corresponding author. Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland.Therapeutic DNAzymes with RNA depleting effect are multifunctional building blocks for constructing biological materials. In a recent work published in Nature Chemistry, Holliger group and Chaput group had a wonderful debate base on previously reported approach for tailoring DNAzymes with high mRNA cleavage activity in mammalian cells. Their perspective pushes the catalytic mechanism investigation of DNAzymes to a new stage with more standardization and clarity.http://www.sciencedirect.com/science/article/pii/S2949723X23000041 |
| spellingShingle | Jiaqi Yan Meixin Ran Hongbo Zhang A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research Biomedical Technology |
| title | A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research |
| title_full | A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research |
| title_fullStr | A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research |
| title_full_unstemmed | A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research |
| title_short | A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research |
| title_sort | scientific debate the sword that cleaves chaos of dnazyme catalysis research |
| url | http://www.sciencedirect.com/science/article/pii/S2949723X23000041 |
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