Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide

An effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2. The corresponding products were obtained in moderate yields with excellent enantioselectivities...

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Main Authors: Dandan Xie, Ying Xie, Yan Ding, Jian Wu, Deyu Hu
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/12/19491
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author Dandan Xie
Ying Xie
Yan Ding
Jian Wu
Deyu Hu
author_facet Dandan Xie
Ying Xie
Yan Ding
Jian Wu
Deyu Hu
author_sort Dandan Xie
collection DOAJ
description An effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2. The corresponding products were obtained in moderate yields with excellent enantioselectivities (up to 99%).
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spelling doaj.art-4d95905aae214411807b5049d00c79b12022-12-22T02:49:36ZengMDPI AGMolecules1420-30492014-11-011912194911950010.3390/molecules191219491molecules191219491Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid SquaramideDandan Xie0Ying Xie1Yan Ding2Jian Wu3Deyu Hu4State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, ChinaState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, ChinaState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, ChinaState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, ChinaState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, ChinaAn effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2. The corresponding products were obtained in moderate yields with excellent enantioselectivities (up to 99%).http://www.mdpi.com/1420-3049/19/12/19491chalcone derivativesenantioselective catalysischiral cinchona alkaloid squaramidesaddition reaction
spellingShingle Dandan Xie
Ying Xie
Yan Ding
Jian Wu
Deyu Hu
Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide
Molecules
chalcone derivatives
enantioselective catalysis
chiral cinchona alkaloid squaramides
addition reaction
title Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide
title_full Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide
title_fullStr Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide
title_full_unstemmed Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide
title_short Synthesis of Chiral Chalcone Derivatives Catalyzed by the Chiral Cinchona Alkaloid Squaramide
title_sort synthesis of chiral chalcone derivatives catalyzed by the chiral cinchona alkaloid squaramide
topic chalcone derivatives
enantioselective catalysis
chiral cinchona alkaloid squaramides
addition reaction
url http://www.mdpi.com/1420-3049/19/12/19491
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AT yingxie synthesisofchiralchalconederivativescatalyzedbythechiralcinchonaalkaloidsquaramide
AT yanding synthesisofchiralchalconederivativescatalyzedbythechiralcinchonaalkaloidsquaramide
AT jianwu synthesisofchiralchalconederivativescatalyzedbythechiralcinchonaalkaloidsquaramide
AT deyuhu synthesisofchiralchalconederivativescatalyzedbythechiralcinchonaalkaloidsquaramide