Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma

Purpose: To report the clinical outcomes of phototherapeutic keratectomy (PTK) for pediatric band keratopathy after treatment for retinoblastoma.Methods: A 5-year-old boy presented with a 2-year history of poor visual acuity and a horizontal gray-white band across the central cornea in the right eye...

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Main Authors: Ruoyan Wei, Meiyan Li, Weiming Yang, Haipeng Xu, Joanne Choi, Xingtao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.668762/full
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author Ruoyan Wei
Ruoyan Wei
Ruoyan Wei
Meiyan Li
Meiyan Li
Meiyan Li
Weiming Yang
Haipeng Xu
Haipeng Xu
Haipeng Xu
Joanne Choi
Xingtao Zhou
Xingtao Zhou
Xingtao Zhou
author_facet Ruoyan Wei
Ruoyan Wei
Ruoyan Wei
Meiyan Li
Meiyan Li
Meiyan Li
Weiming Yang
Haipeng Xu
Haipeng Xu
Haipeng Xu
Joanne Choi
Xingtao Zhou
Xingtao Zhou
Xingtao Zhou
author_sort Ruoyan Wei
collection DOAJ
description Purpose: To report the clinical outcomes of phototherapeutic keratectomy (PTK) for pediatric band keratopathy after treatment for retinoblastoma.Methods: A 5-year-old boy presented with a 2-year history of poor visual acuity and a horizontal gray-white band across the central cornea in the right eye. He was diagnosed with band keratopathy after chemo-laser-cryotherapy for retinoblastoma. The band keratopathy was treated via PTK using the Mel-90 excimer laser with an optical treatment zone of 7.0 mm and ablation depth of 120 μm. The patient was followed at 1 week and 3 months postoperatively.Results: Surgery and postoperative follow-up were uneventful. At the 3-month follow-up, the uncorrected distant visual acuity of the right eye improved to 20/125, and the corrected distance visual acuity improved to 20/70 with a refraction of +10.00 D/−2.50 DC × 15. The clarity of the ablated area was evidently improved. The central corneal thickness decreases from 612 to 584 μm. The optical coherence tomography showed the thin band of hyperreflectivity in the ablated area disappeared, corneal transparency improved and the corneal surface smoothened.Conclusions: PTK is a safe and effective procedure to treat band keratopathy following treatment of retinoblastoma in children. Early intervention can reduce the risk of developing deprivation amblyopia.
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spelling doaj.art-4d9acd664de3448ab85818cfd455c9132022-12-21T18:34:05ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-08-01810.3389/fmed.2021.668762668762Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for RetinoblastomaRuoyan Wei0Ruoyan Wei1Ruoyan Wei2Meiyan Li3Meiyan Li4Meiyan Li5Weiming Yang6Haipeng Xu7Haipeng Xu8Haipeng Xu9Joanne Choi10Xingtao Zhou11Xingtao Zhou12Xingtao Zhou13Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNHC Key Laboratory of Myopia (Fudan University), Shanghai, ChinaShanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNHC Key Laboratory of Myopia (Fudan University), Shanghai, ChinaShanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaDepartment of Ophthalmology, Children's Hospital of Fudan University, Shanghai, ChinaDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNHC Key Laboratory of Myopia (Fudan University), Shanghai, ChinaShanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaKresge Eye Institute/Department of Ophthalmology, Wayne State University, Detroit, MI, United StatesDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, ChinaNHC Key Laboratory of Myopia (Fudan University), Shanghai, ChinaShanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaPurpose: To report the clinical outcomes of phototherapeutic keratectomy (PTK) for pediatric band keratopathy after treatment for retinoblastoma.Methods: A 5-year-old boy presented with a 2-year history of poor visual acuity and a horizontal gray-white band across the central cornea in the right eye. He was diagnosed with band keratopathy after chemo-laser-cryotherapy for retinoblastoma. The band keratopathy was treated via PTK using the Mel-90 excimer laser with an optical treatment zone of 7.0 mm and ablation depth of 120 μm. The patient was followed at 1 week and 3 months postoperatively.Results: Surgery and postoperative follow-up were uneventful. At the 3-month follow-up, the uncorrected distant visual acuity of the right eye improved to 20/125, and the corrected distance visual acuity improved to 20/70 with a refraction of +10.00 D/−2.50 DC × 15. The clarity of the ablated area was evidently improved. The central corneal thickness decreases from 612 to 584 μm. The optical coherence tomography showed the thin band of hyperreflectivity in the ablated area disappeared, corneal transparency improved and the corneal surface smoothened.Conclusions: PTK is a safe and effective procedure to treat band keratopathy following treatment of retinoblastoma in children. Early intervention can reduce the risk of developing deprivation amblyopia.https://www.frontiersin.org/articles/10.3389/fmed.2021.668762/fullphototherapeutic keratectomy (PTK)band keratopathyretinoblastomatreatmentvisual outcome
spellingShingle Ruoyan Wei
Ruoyan Wei
Ruoyan Wei
Meiyan Li
Meiyan Li
Meiyan Li
Weiming Yang
Haipeng Xu
Haipeng Xu
Haipeng Xu
Joanne Choi
Xingtao Zhou
Xingtao Zhou
Xingtao Zhou
Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma
Frontiers in Medicine
phototherapeutic keratectomy (PTK)
band keratopathy
retinoblastoma
treatment
visual outcome
title Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma
title_full Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma
title_fullStr Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma
title_full_unstemmed Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma
title_short Case Report: Phototherapeutic Keratectomy for Band Keratopathy Secondary to Chemo-Laser-Cryotherapy for Retinoblastoma
title_sort case report phototherapeutic keratectomy for band keratopathy secondary to chemo laser cryotherapy for retinoblastoma
topic phototherapeutic keratectomy (PTK)
band keratopathy
retinoblastoma
treatment
visual outcome
url https://www.frontiersin.org/articles/10.3389/fmed.2021.668762/full
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