Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation

Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation

ABSTRACT Multiple molecular assays now enable high-throughput profiling of the ecology, metabolic capacity, and activity of the human microbiome. However, to date, analyses of such multi-omic data typically focus on statistical associations, often ignoring extensive prior knowledge of the mechanisms...

Full description

Bibliographic Details
Main Authors: Cecilia Noecker, Alexander Eng, Sujatha Srinivasan, Casey M. Theriot, Vincent B. Young, Janet K. Jansson, David N. Fredricks, Elhanan Borenstein
Format: Article
Language:English
Published: American Society for Microbiology 2016-02-01
Series:mSystems
Subjects:
microbiome
multi-omic
metabolic modeling
community composition
metabolomics
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00013-15

Internet

https://journals.asm.org/doi/10.1128/mSystems.00013-15

Similar Items