TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
Low-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medi...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2014-06-01
|
| Series: | Cells |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2073-4409/3/3/662 |
| _version_ | 1797728481193230336 |
|---|---|
| author | Lina Wang Di Zhang Wolfgang Schwarz |
| author_facet | Lina Wang Di Zhang Wolfgang Schwarz |
| author_sort | Lina Wang |
| collection | DOAJ |
| description | Low-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medical effects. We suggest that activation of TRPV channels in the mast cells forms a basis for the underlying mechanisms and that released ATP and histamine may be putative mediators for therapeutic effects. |
| first_indexed | 2024-03-12T11:14:39Z |
| format | Article |
| id | doaj.art-4d9fe6180e1e45ab9844b3f0cc13620d |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-12T11:14:39Z |
| publishDate | 2014-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-4d9fe6180e1e45ab9844b3f0cc13620d2023-09-02T02:12:43ZengMDPI AGCells2073-44092014-06-013366267310.3390/cells3030662cells3030662TRPV Channels in Mast Cells as a Target for Low-Level-Laser TherapyLina Wang0Di Zhang1Wolfgang Schwarz2Shanghai University of Traditional Chinese Medicine and Shanghai Research Center for Acupuncture and Meridians, Shanghai 201203, ChinaDepartment of Mechanics and Engineering Science, Fudan University Shanghai, Shanghai 201203, ChinaInstitute for Biophysics, Goethe-University Frankfurt am Main, 60438 Frankfurt, GermanyLow-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medical effects. We suggest that activation of TRPV channels in the mast cells forms a basis for the underlying mechanisms and that released ATP and histamine may be putative mediators for therapeutic effects.http://www.mdpi.com/2073-4409/3/3/662laser lightTRPV activationmast-cell degranulationATPCa2+histamine |
| spellingShingle | Lina Wang Di Zhang Wolfgang Schwarz TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy Cells laser light TRPV activation mast-cell degranulation ATP Ca2+ histamine |
| title | TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy |
| title_full | TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy |
| title_fullStr | TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy |
| title_full_unstemmed | TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy |
| title_short | TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy |
| title_sort | trpv channels in mast cells as a target for low level laser therapy |
| topic | laser light TRPV activation mast-cell degranulation ATP Ca2+ histamine |
| url | http://www.mdpi.com/2073-4409/3/3/662 |
| work_keys_str_mv | AT linawang trpvchannelsinmastcellsasatargetforlowlevellasertherapy AT dizhang trpvchannelsinmastcellsasatargetforlowlevellasertherapy AT wolfgangschwarz trpvchannelsinmastcellsasatargetforlowlevellasertherapy |