Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

Abstract Background: Visceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong limitations, especially high toxicity. In this context, natural products are important sources of new drug alternatives for VL therapy. The...

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Bibliographic Details
Main Authors:	Thais A. da Costa-Silva, Geanne A. Alves Conserva, Andrés J. Galisteo Jr, Andre G. Tempone, João Henrique G. Lago
Format:	Article
Language:	English
Published:	SciELO
Series:	Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:	Leishmania (L.) infantum chagasi Antileishmanial Nectandra oppositifolia Secosubamolide Immunomodulatory
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100317&lng=en&tlng=en

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