Distinct characteristics of the DNA damage response in mammalian oocytes

Abstract DNA damage is a critical threat that poses significant challenges to all cells. To address this issue, cells have evolved a sophisticated molecular and cellular process known as the DNA damage response (DDR). Among the various cell types, mammalian oocytes, which remain dormant in the ovary...

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Bibliographic Details
Main Authors: Jiyeon Leem, Crystal Lee, Da Yi Choi, Jeong Su Oh
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01178-2