Wounding the stroma: Docetaxel's role in dormant breast cancer escape.
The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-09-01
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| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002297&type=printable |
| _version_ | 1797668301991575552 |
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| author | Tyler T Cooper Lynne-Marie Postovit |
| author_facet | Tyler T Cooper Lynne-Marie Postovit |
| author_sort | Tyler T Cooper |
| collection | DOAJ |
| description | The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells. |
| first_indexed | 2024-03-11T20:27:09Z |
| format | Article |
| id | doaj.art-4da6dfdabce547c7a6c8c4dec6477107 |
| institution | Directory Open Access Journal |
| issn | 1544-9173 1545-7885 |
| language | English |
| last_indexed | 2024-03-11T20:27:09Z |
| publishDate | 2023-09-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Biology |
| spelling | doaj.art-4da6dfdabce547c7a6c8c4dec64771072023-10-02T12:17:13ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852023-09-01219e300229710.1371/journal.pbio.3002297Wounding the stroma: Docetaxel's role in dormant breast cancer escape.Tyler T CooperLynne-Marie PostovitThe mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002297&type=printable |
| spellingShingle | Tyler T Cooper Lynne-Marie Postovit Wounding the stroma: Docetaxel's role in dormant breast cancer escape. PLoS Biology |
| title | Wounding the stroma: Docetaxel's role in dormant breast cancer escape. |
| title_full | Wounding the stroma: Docetaxel's role in dormant breast cancer escape. |
| title_fullStr | Wounding the stroma: Docetaxel's role in dormant breast cancer escape. |
| title_full_unstemmed | Wounding the stroma: Docetaxel's role in dormant breast cancer escape. |
| title_short | Wounding the stroma: Docetaxel's role in dormant breast cancer escape. |
| title_sort | wounding the stroma docetaxel s role in dormant breast cancer escape |
| url | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002297&type=printable |
| work_keys_str_mv | AT tylertcooper woundingthestromadocetaxelsroleindormantbreastcancerescape AT lynnemariepostovit woundingthestromadocetaxelsroleindormantbreastcancerescape |