Brucellosis; Difficulty of Diagnosis in Endemic Areas
Introduction: Brucellosis is a zoonotic disease distributed worldwide and very important public health problem especially in the developing countries. In this study, we aimed to evaluate the clinical/laboratory findings of brucellosis patients and contribute of coombs testing to diagnosis at Iğdır S...
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| Format: | Article |
| Language: | English |
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Rabia Yılmaz
2023-03-01
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| Series: | Journal of Contemporary Medicine |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/2673364 |
| _version_ | 1797860747969036288 |
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| author | Gülay Dede Yunus Gürbüz Emin Ediz Tütüncü Ferit Kuşcu Asli Haykır Solay |
| author_facet | Gülay Dede Yunus Gürbüz Emin Ediz Tütüncü Ferit Kuşcu Asli Haykır Solay |
| author_sort | Gülay Dede |
| collection | DOAJ |
| description | Introduction: Brucellosis is a zoonotic disease distributed worldwide and very important public health problem especially in the developing countries. In this study, we aimed to evaluate the clinical/laboratory findings of brucellosis patients and contribute of coombs testing to diagnosis at Iğdır State Hospital infection diseases and clinical microbiology department.
Materials and Methods: One hundred and forty-five brucellosis patients followed up in our clinic between September 2012 and February 2013 were evaluated retrospectively. Demographic characteristics, laboratory findings, diagnostic methods of the patients were presented.
Results: The mean age of the patients were 39±15 (18-80) and 59% (n=86) of the patients were female, 41% (n=59) were male. Most frequent risk factors were animal breeding (n=115, 79%) and using underdone milk and milk products (n=98, 69%). Most reported complaints were weakness (92%), arthralgia (89%), sweating (74%), lack of appetite (70%) and fever (68%). Fifty-seven of the brucellosis patients could not diagnosed with standard tube agglutination. Therefore, Coombs test was used for these undiagnosed patients (39%, n=57). Eighty patients were evaluated as acute (55%), 53 as subacute (37%) and 12 as chronic (8%) brucellosis.
Conclusions: Brucellosis can affect all organ systems and cause different clinical manifestations. Therefore, difficulties are encountered in the diagnosis of the disease. Brucellosis should be kept in mind in the differential diagnosis especially in the endemic regions. When the clinical suspicion exists detailed laboratory evaluation must be performed. |
| first_indexed | 2024-04-09T21:50:43Z |
| format | Article |
| id | doaj.art-4dab0a433da1471397923b9260217ed5 |
| institution | Directory Open Access Journal |
| issn | 2667-7180 |
| language | English |
| last_indexed | 2024-04-09T21:50:43Z |
| publishDate | 2023-03-01 |
| publisher | Rabia Yılmaz |
| record_format | Article |
| series | Journal of Contemporary Medicine |
| spelling | doaj.art-4dab0a433da1471397923b9260217ed52023-03-24T19:43:20ZengRabia YılmazJournal of Contemporary Medicine2667-71802023-03-0113228228710.16899/jcm.11806771809Brucellosis; Difficulty of Diagnosis in Endemic AreasGülay Dede0Yunus Gürbüz1Emin Ediz Tütüncü2Ferit Kuşcu3Asli Haykır Solay4Diyarbakır Gazi Yaşargil Eğitim Ve Araştırma HastanesiDIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİDIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİÇukurova Üniversitesi Tıp FakültesiANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİIntroduction: Brucellosis is a zoonotic disease distributed worldwide and very important public health problem especially in the developing countries. In this study, we aimed to evaluate the clinical/laboratory findings of brucellosis patients and contribute of coombs testing to diagnosis at Iğdır State Hospital infection diseases and clinical microbiology department. Materials and Methods: One hundred and forty-five brucellosis patients followed up in our clinic between September 2012 and February 2013 were evaluated retrospectively. Demographic characteristics, laboratory findings, diagnostic methods of the patients were presented. Results: The mean age of the patients were 39±15 (18-80) and 59% (n=86) of the patients were female, 41% (n=59) were male. Most frequent risk factors were animal breeding (n=115, 79%) and using underdone milk and milk products (n=98, 69%). Most reported complaints were weakness (92%), arthralgia (89%), sweating (74%), lack of appetite (70%) and fever (68%). Fifty-seven of the brucellosis patients could not diagnosed with standard tube agglutination. Therefore, Coombs test was used for these undiagnosed patients (39%, n=57). Eighty patients were evaluated as acute (55%), 53 as subacute (37%) and 12 as chronic (8%) brucellosis. Conclusions: Brucellosis can affect all organ systems and cause different clinical manifestations. Therefore, difficulties are encountered in the diagnosis of the disease. Brucellosis should be kept in mind in the differential diagnosis especially in the endemic regions. When the clinical suspicion exists detailed laboratory evaluation must be performed.https://dergipark.org.tr/tr/download/article-file/2673364brucellosisdiagnosiscoombs test.bruselloztanıcoombs testi |
| spellingShingle | Gülay Dede Yunus Gürbüz Emin Ediz Tütüncü Ferit Kuşcu Asli Haykır Solay Brucellosis; Difficulty of Diagnosis in Endemic Areas Journal of Contemporary Medicine brucellosis diagnosis coombs test. bruselloz tanı coombs testi |
| title | Brucellosis; Difficulty of Diagnosis in Endemic Areas |
| title_full | Brucellosis; Difficulty of Diagnosis in Endemic Areas |
| title_fullStr | Brucellosis; Difficulty of Diagnosis in Endemic Areas |
| title_full_unstemmed | Brucellosis; Difficulty of Diagnosis in Endemic Areas |
| title_short | Brucellosis; Difficulty of Diagnosis in Endemic Areas |
| title_sort | brucellosis difficulty of diagnosis in endemic areas |
| topic | brucellosis diagnosis coombs test. bruselloz tanı coombs testi |
| url | https://dergipark.org.tr/tr/download/article-file/2673364 |
| work_keys_str_mv | AT gulaydede brucellosisdifficultyofdiagnosisinendemicareas AT yunusgurbuz brucellosisdifficultyofdiagnosisinendemicareas AT eminediztutuncu brucellosisdifficultyofdiagnosisinendemicareas AT feritkuscu brucellosisdifficultyofdiagnosisinendemicareas AT aslihaykırsolay brucellosisdifficultyofdiagnosisinendemicareas |