Naringin ameliorates the high glucose-induced rat mesangial cell inflammatory reaction by modulating the NLRP3 Inflammasome

Naringin ameliorates the high glucose-induced rat mesangial cell inflammatory reaction by modulating the NLRP3 Inflammasome

Abstract Background The Nucleotide binding and oligomerization domain-like receptorfamily pyrin domain-containing 3 (NLRP3)-inflammasome plays an important role in various diseases, including a variety of kidney diseases. Naringin exhibits anti-inflammatory and anti-oxidation effects among others, b...

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Bibliographic Details
Main Authors: Fenqin Chen, Guozhu Wei, Jiao Xu, Xiaoyu Ma, Qiuyue Wang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Diabetes mellitus
Diabetic kidney disease
NLRP3 inflammasome
NLRP3-caspase-1-IL-1β/IL-18 signaling pathway
Naringin
Online Access:http://link.springer.com/article/10.1186/s12906-018-2257-y

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