Cryptococcus gattii strains with a high phagocytosis phenotype by macrophages display high pathogenicity at the early stage of infection in vivo

Cryptococcus gattii strains with a high phagocytosis phenotype by macrophages display high pathogenicity at the early stage of infection in vivo

Cryptococcus gattii (Cg) is a facultative intracellular pathogen that can replicate and disseminate in mammalian macrophages, causing life-threatening cryptococcosis in both immunocompetent and immunocompromised individuals. Cryptococcus-macrophage interactions are crucial for cryptococcosis prognos...

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Bibliographic Details
Main Authors: Yang Chen, Shen Wanjun, Wang Lifeng, Zang Xuelei, Huang Yemei, Deng Hengyu, Zhou Yangyu, Xie Mei, Xue Xinying, Shen Dingxia
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-10-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
<italic>Cryptococcus gattii</italic>
macrophage
phagocytosis
pathogenicity
granuloma
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023250

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