Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity
Modern robotic hands/upper limbs may replace multiple degrees of freedom of extremity function. However, their intuitive use requires a high number of control signals, which current man-machine interfaces do not provide. Here, we discuss a broadband control interface that combines targeted muscle re...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2017-07-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fnins.2017.00421/full |
| _version_ | 1819051705342361600 |
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| author | Konstantin D. Bergmeister Konstantin D. Bergmeister Ivan Vujaklija Silvia Muceli Agnes Sturma Agnes Sturma Laura A. Hruby Cosima Prahm Otto Riedl Otto Riedl Stefan Salminger Stefan Salminger Krisztina Manzano-Szalai Martin Aman Michael-Friedrich Russold Christian Hofer Christian Hofer Jose Principe Dario Farina Oskar C. Aszmann Oskar C. Aszmann |
| author_facet | Konstantin D. Bergmeister Konstantin D. Bergmeister Ivan Vujaklija Silvia Muceli Agnes Sturma Agnes Sturma Laura A. Hruby Cosima Prahm Otto Riedl Otto Riedl Stefan Salminger Stefan Salminger Krisztina Manzano-Szalai Martin Aman Michael-Friedrich Russold Christian Hofer Christian Hofer Jose Principe Dario Farina Oskar C. Aszmann Oskar C. Aszmann |
| author_sort | Konstantin D. Bergmeister |
| collection | DOAJ |
| description | Modern robotic hands/upper limbs may replace multiple degrees of freedom of extremity function. However, their intuitive use requires a high number of control signals, which current man-machine interfaces do not provide. Here, we discuss a broadband control interface that combines targeted muscle reinnervation, implantable multichannel electromyographic sensors, and advanced decoding to address the increasing capabilities of modern robotic limbs. With targeted muscle reinnervation, nerves that have lost their targets due to an amputation are surgically transferred to residual stump muscles to increase the number of intuitive prosthetic control signals. This surgery re-establishes a nerve-muscle connection that is used for sensing nerve activity with myoelectric interfaces. Moreover, the nerve transfer determines neurophysiological effects, such as muscular hyper-reinnervation and cortical reafferentation that can be exploited by the myoelectric interface. Modern implantable multichannel EMG sensors provide signals from which it is possible to disentangle the behavior of single motor neurons. Recent studies have shown that the neural drive to muscles can be decoded from these signals and thereby the user's intention can be reliably estimated. By combining these concepts in chronic implants and embedded electronics, we believe that it is in principle possible to establish a broadband man-machine interface, with specific applications in prosthesis control. This perspective illustrates this concept, based on combining advanced surgical techniques with recording hardware and processing algorithms. Here we describe the scientific evidence for this concept, current state of investigations, challenges, and alternative approaches to improve current prosthetic interfaces. |
| first_indexed | 2024-12-21T12:08:11Z |
| format | Article |
| id | doaj.art-4db16f7721da4df8ba6db286b18de8ef |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-21T12:08:11Z |
| publishDate | 2017-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-4db16f7721da4df8ba6db286b18de8ef2022-12-21T19:04:39ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2017-07-011110.3389/fnins.2017.00421263204Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron ActivityKonstantin D. Bergmeister0Konstantin D. Bergmeister1Ivan Vujaklija2Silvia Muceli3Agnes Sturma4Agnes Sturma5Laura A. Hruby6Cosima Prahm7Otto Riedl8Otto Riedl9Stefan Salminger10Stefan Salminger11Krisztina Manzano-Szalai12Martin Aman13Michael-Friedrich Russold14Christian Hofer15Christian Hofer16Jose Principe17Dario Farina18Oskar C. Aszmann19Oskar C. Aszmann20CD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaDepartment of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Plastic and Hand Surgery, University of HeidelbergLudwigshafen, GermanyDepartment of Bioengineering, Centre for Neurotechnology, Imperial College LondonLondon, United KingdomNeurorehabilitation Systems Research Group, Clinic for Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center GöttingenGöttingen, GermanyCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaHealth Assisting Engineering, University of Applied Sciences WienVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of ViennaVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of ViennaVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaOtto Bock Healthcare Products GmbHVienna, AustriaCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaOtto Bock Healthcare Products GmbHVienna, AustriaDepartment of Electrical and Computer Engineering, University of FloridaGainesville, FL, United StatesDepartment of Bioengineering, Centre for Neurotechnology, Imperial College LondonLondon, United KingdomCD-Laboratory for the Restoration of Extremity Function, Department of Surgery, Medical University of ViennaVienna, AustriaDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of ViennaVienna, AustriaModern robotic hands/upper limbs may replace multiple degrees of freedom of extremity function. However, their intuitive use requires a high number of control signals, which current man-machine interfaces do not provide. Here, we discuss a broadband control interface that combines targeted muscle reinnervation, implantable multichannel electromyographic sensors, and advanced decoding to address the increasing capabilities of modern robotic limbs. With targeted muscle reinnervation, nerves that have lost their targets due to an amputation are surgically transferred to residual stump muscles to increase the number of intuitive prosthetic control signals. This surgery re-establishes a nerve-muscle connection that is used for sensing nerve activity with myoelectric interfaces. Moreover, the nerve transfer determines neurophysiological effects, such as muscular hyper-reinnervation and cortical reafferentation that can be exploited by the myoelectric interface. Modern implantable multichannel EMG sensors provide signals from which it is possible to disentangle the behavior of single motor neurons. Recent studies have shown that the neural drive to muscles can be decoded from these signals and thereby the user's intention can be reliably estimated. By combining these concepts in chronic implants and embedded electronics, we believe that it is in principle possible to establish a broadband man-machine interface, with specific applications in prosthesis control. This perspective illustrates this concept, based on combining advanced surgical techniques with recording hardware and processing algorithms. Here we describe the scientific evidence for this concept, current state of investigations, challenges, and alternative approaches to improve current prosthetic interfaces.http://journal.frontiersin.org/article/10.3389/fnins.2017.00421/fullmyoelectric prosthesisprosthetic interfaceEMGnerve transfersTMRtargeted muscle reinnervation |
| spellingShingle | Konstantin D. Bergmeister Konstantin D. Bergmeister Ivan Vujaklija Silvia Muceli Agnes Sturma Agnes Sturma Laura A. Hruby Cosima Prahm Otto Riedl Otto Riedl Stefan Salminger Stefan Salminger Krisztina Manzano-Szalai Martin Aman Michael-Friedrich Russold Christian Hofer Christian Hofer Jose Principe Dario Farina Oskar C. Aszmann Oskar C. Aszmann Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity Frontiers in Neuroscience myoelectric prosthesis prosthetic interface EMG nerve transfers TMR targeted muscle reinnervation |
| title | Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity |
| title_full | Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity |
| title_fullStr | Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity |
| title_full_unstemmed | Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity |
| title_short | Broadband Prosthetic Interfaces: Combining Nerve Transfers and Implantable Multichannel EMG Technology to Decode Spinal Motor Neuron Activity |
| title_sort | broadband prosthetic interfaces combining nerve transfers and implantable multichannel emg technology to decode spinal motor neuron activity |
| topic | myoelectric prosthesis prosthetic interface EMG nerve transfers TMR targeted muscle reinnervation |
| url | http://journal.frontiersin.org/article/10.3389/fnins.2017.00421/full |
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