Comparable level of aggression between patients with behavioural addiction and healthy subjects
Abstract Heightened aggression is identified in several psychiatric disorders, including addiction. In this preliminary study with a relatively small number of samples, aggression in subjects diagnosed with behavioural addiction (BA) was implicitly assessed using the point subtraction aggression par...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-07-01
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| Series: | Translational Psychiatry |
| Online Access: | https://doi.org/10.1038/s41398-021-01502-8 |
| _version_ | 1819103915196547072 |
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| author | Yui Asaoka Moojun Won Tomonari Morita Emi Ishikawa Yukiori Goto |
| author_facet | Yui Asaoka Moojun Won Tomonari Morita Emi Ishikawa Yukiori Goto |
| author_sort | Yui Asaoka |
| collection | DOAJ |
| description | Abstract Heightened aggression is identified in several psychiatric disorders, including addiction. In this preliminary study with a relatively small number of samples, aggression in subjects diagnosed with behavioural addiction (BA) was implicitly assessed using the point subtraction aggression paradigm (PSAP) test along with measurements of oxy- and deoxyhaemoglobin dynamics in the prefrontal cortex (PFC) during the test using functional near-infrared spectroscopy. Aggression in BA patients was no higher than that of healthy control (CT) subjects in the PSAP test. Although no apparent increase or decrease in haemoglobin concentrations was observed in the PFC of either BA patients or CT subjects, abnormal correlations within the PFC network were present in BA patients. Consistent with comparable aggression between the groups, blood concentrations of the sex hormone testosterone, which has been shown to be associated with aggressiveness, was even lower in BA patients than in CT subjects. In contrast, when a set of questionnaire surveys for the assessment of aggression were administered, BA patients rated themselves as more aggressive than non-BA subjects. Collectively, these results suggest that aggression may not be heightened in BA, but BA patients may overestimate their aggressiveness, raising concerns about the use of questionnaire surveys for assessments of affective traits such as aggression in behavioural addiction. |
| first_indexed | 2024-12-22T01:58:02Z |
| format | Article |
| id | doaj.art-4db18c7ba3534a8985e2bdbf3fcbf10e |
| institution | Directory Open Access Journal |
| issn | 2158-3188 |
| language | English |
| last_indexed | 2024-12-22T01:58:02Z |
| publishDate | 2021-07-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Translational Psychiatry |
| spelling | doaj.art-4db18c7ba3534a8985e2bdbf3fcbf10e2022-12-21T18:42:43ZengNature Publishing GroupTranslational Psychiatry2158-31882021-07-0111111010.1038/s41398-021-01502-8Comparable level of aggression between patients with behavioural addiction and healthy subjectsYui Asaoka0Moojun Won1Tomonari Morita2Emi Ishikawa3Yukiori Goto4Primate Research Institute, Kyoto UniversityKyowa HospitalKyowa HospitalKyowa HospitalPrimate Research Institute, Kyoto UniversityAbstract Heightened aggression is identified in several psychiatric disorders, including addiction. In this preliminary study with a relatively small number of samples, aggression in subjects diagnosed with behavioural addiction (BA) was implicitly assessed using the point subtraction aggression paradigm (PSAP) test along with measurements of oxy- and deoxyhaemoglobin dynamics in the prefrontal cortex (PFC) during the test using functional near-infrared spectroscopy. Aggression in BA patients was no higher than that of healthy control (CT) subjects in the PSAP test. Although no apparent increase or decrease in haemoglobin concentrations was observed in the PFC of either BA patients or CT subjects, abnormal correlations within the PFC network were present in BA patients. Consistent with comparable aggression between the groups, blood concentrations of the sex hormone testosterone, which has been shown to be associated with aggressiveness, was even lower in BA patients than in CT subjects. In contrast, when a set of questionnaire surveys for the assessment of aggression were administered, BA patients rated themselves as more aggressive than non-BA subjects. Collectively, these results suggest that aggression may not be heightened in BA, but BA patients may overestimate their aggressiveness, raising concerns about the use of questionnaire surveys for assessments of affective traits such as aggression in behavioural addiction.https://doi.org/10.1038/s41398-021-01502-8 |
| spellingShingle | Yui Asaoka Moojun Won Tomonari Morita Emi Ishikawa Yukiori Goto Comparable level of aggression between patients with behavioural addiction and healthy subjects Translational Psychiatry |
| title | Comparable level of aggression between patients with behavioural addiction and healthy subjects |
| title_full | Comparable level of aggression between patients with behavioural addiction and healthy subjects |
| title_fullStr | Comparable level of aggression between patients with behavioural addiction and healthy subjects |
| title_full_unstemmed | Comparable level of aggression between patients with behavioural addiction and healthy subjects |
| title_short | Comparable level of aggression between patients with behavioural addiction and healthy subjects |
| title_sort | comparable level of aggression between patients with behavioural addiction and healthy subjects |
| url | https://doi.org/10.1038/s41398-021-01502-8 |
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