Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey
Background: Associations have been reported between lifestyle-related diseases and evacuation after the Great East Japan Earthquake (GEJE). However, the relationship between lifestyle-related diseases and the effective radiation dose due to external exposure (EDEE) after the GEJE remains unclear. Me...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Japan Epidemiological Association
2022-12-01
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| Series: | Journal of Epidemiology |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jea/32/Supplement_XII/32_JE20210286/_pdf |
| _version_ | 1811208916661436416 |
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| author | Akira Sakai Masanori Nagao Hironori Nakano Tetsuya Ohira Tetsuo Ishikawa Mitsuaki Hosoya Michio Shimabukuro Atsushi Takahashi Junichiro J. Kazama Kanako Okazaki Fumikazu Hayashi Seiji Yasumura Hitoshi Ohto Kenji Kamiya |
| author_facet | Akira Sakai Masanori Nagao Hironori Nakano Tetsuya Ohira Tetsuo Ishikawa Mitsuaki Hosoya Michio Shimabukuro Atsushi Takahashi Junichiro J. Kazama Kanako Okazaki Fumikazu Hayashi Seiji Yasumura Hitoshi Ohto Kenji Kamiya |
| author_sort | Akira Sakai |
| collection | DOAJ |
| description | Background: Associations have been reported between lifestyle-related diseases and evacuation after the Great East Japan Earthquake (GEJE). However, the relationship between lifestyle-related diseases and the effective radiation dose due to external exposure (EDEE) after the GEJE remains unclear. Methods: From among 72,869 residents of Fukushima Prefecture (31,982 men; 40,887 women) who underwent a comprehensive health check in fiscal year (FY) 2011, the data of 54,087 residents (22,599 men; 31,488 women) aged 16 to 84 years were analyzed. The EDEE data of 25,685 residents with incomplete results from the basic survey, performed to estimate the external radiation exposure dose, were supplemented using multiple imputation. The data were classified into three groups based on EDEE (0 to <1, 1 to <2, and ≥2 mSv groups and associations between the incidence of diseases and EDEE from FY2011 to FY2017 were examined using a Cox proportional hazards model, with FY2011 as the baseline. Results: A higher EDEE was associated with a greater incidence of hypertension, diabetes mellitus, dyslipidemia, hyperuricemia, liver dysfunction, and polycythemia from FY2011 to FY2017 in the age- and sex-adjusted model. However, after further adjustment for evacuation status and lifestyle-related factors, the significant associations disappeared. No association was found between EDEE and other lifestyle-related diseases. Conclusion: EDEE was not directly associated with the incidence of lifestyle-related diseases after the GEJE. However, residents with higher external radiation doses in Fukushima Prefecture might suffer from lifestyle-related diseases related to evacuation and the resultant lifestyle changes. |
| first_indexed | 2024-04-12T04:29:52Z |
| format | Article |
| id | doaj.art-4db418b724974d3897cd04601e49f4d1 |
| institution | Directory Open Access Journal |
| issn | 0917-5040 1349-9092 |
| language | English |
| last_indexed | 2024-04-12T04:29:52Z |
| publishDate | 2022-12-01 |
| publisher | Japan Epidemiological Association |
| record_format | Article |
| series | Journal of Epidemiology |
| spelling | doaj.art-4db418b724974d3897cd04601e49f4d12022-12-22T03:47:57ZengJapan Epidemiological AssociationJournal of Epidemiology0917-50401349-90922022-12-0132Suppl 12S84S9410.2188/jea.JE20210286Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management SurveyAkira Sakai0Masanori Nagao1Hironori Nakano2Tetsuya Ohira3Tetsuo Ishikawa4Mitsuaki Hosoya5Michio Shimabukuro6Atsushi Takahashi7Junichiro J. Kazama8Kanako Okazaki9Fumikazu Hayashi10Seiji Yasumura11Hitoshi Ohto12Kenji Kamiya13Department of Radiation Life Sciences, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Radiation Physics and Chemistry, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Diabetes, Endocrinology and Metabolism, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Physical Therapy, Fukushima Medical University School of Health Sciences, Fukushima, JapanDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, JapanDepartment of Public Health, Fukushima Medical University School of Medicine, Fukushima, JapanRadiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, JapanRadiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Fukushima, JapanBackground: Associations have been reported between lifestyle-related diseases and evacuation after the Great East Japan Earthquake (GEJE). However, the relationship between lifestyle-related diseases and the effective radiation dose due to external exposure (EDEE) after the GEJE remains unclear. Methods: From among 72,869 residents of Fukushima Prefecture (31,982 men; 40,887 women) who underwent a comprehensive health check in fiscal year (FY) 2011, the data of 54,087 residents (22,599 men; 31,488 women) aged 16 to 84 years were analyzed. The EDEE data of 25,685 residents with incomplete results from the basic survey, performed to estimate the external radiation exposure dose, were supplemented using multiple imputation. The data were classified into three groups based on EDEE (0 to <1, 1 to <2, and ≥2 mSv groups and associations between the incidence of diseases and EDEE from FY2011 to FY2017 were examined using a Cox proportional hazards model, with FY2011 as the baseline. Results: A higher EDEE was associated with a greater incidence of hypertension, diabetes mellitus, dyslipidemia, hyperuricemia, liver dysfunction, and polycythemia from FY2011 to FY2017 in the age- and sex-adjusted model. However, after further adjustment for evacuation status and lifestyle-related factors, the significant associations disappeared. No association was found between EDEE and other lifestyle-related diseases. Conclusion: EDEE was not directly associated with the incidence of lifestyle-related diseases after the GEJE. However, residents with higher external radiation doses in Fukushima Prefecture might suffer from lifestyle-related diseases related to evacuation and the resultant lifestyle changes.https://www.jstage.jst.go.jp/article/jea/32/Supplement_XII/32_JE20210286/_pdfcomprehensive health checkexternal radiation exposure doselifestyle-related diseaselymphopenianeutropenia |
| spellingShingle | Akira Sakai Masanori Nagao Hironori Nakano Tetsuya Ohira Tetsuo Ishikawa Mitsuaki Hosoya Michio Shimabukuro Atsushi Takahashi Junichiro J. Kazama Kanako Okazaki Fumikazu Hayashi Seiji Yasumura Hitoshi Ohto Kenji Kamiya Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey Journal of Epidemiology comprehensive health check external radiation exposure dose lifestyle-related disease lymphopenia neutropenia |
| title | Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey |
| title_full | Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey |
| title_fullStr | Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey |
| title_full_unstemmed | Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey |
| title_short | Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey |
| title_sort | effects of external radiation exposure resulting from the fukushima daiichi nuclear power plant accident on the health of residents in the evacuation zones the fukushima health management survey |
| topic | comprehensive health check external radiation exposure dose lifestyle-related disease lymphopenia neutropenia |
| url | https://www.jstage.jst.go.jp/article/jea/32/Supplement_XII/32_JE20210286/_pdf |
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